1-(3-Hydroxymethylpyridin-2-yl)-4-methyl-2-phenylpiperazine CAS 61337-89-1

I-1-(3-Hydroxymethylpyridin-2-yl)-4-methyl-2-phenylpiperazine CAS 61337-89-1 yethula

Okomzimba
Ukubukeka: Ngaphansi kwezimo ezijwayelekile, kungenzeka kube yikristalu eqinile, kodwa i-crystal morphology ethize, umbala neminye imininingwane idinga ukuhlanganiswa nokubhekwa kwesibonakhulu sochwepheshe kanye nedatha yezincwadi ukuze kuchazwe ngokunembile. Ukubukeka okuqinile kunquma ukuthi kusebenza kanjani ngesikhathi sokugcina, ukuthutha nokufinyelela, isibonelo, izinto eziqinile ze-crystalline zifaneleka kakhulu ukusetshenziswa nge-spatula.
I-Solubility: Ezincibilikilweni ezivamile ze-organic, njenge-ethanol ne-methylene chloride, ingase ibonise amazinga ahlukene okuncibilika. Idatha ye-solubility kuzincibilikisi zemvelo ibaluleke kakhulu ocwaningweni lwe-organic synthesis lusetshenziswa njengempahla eluhlaza noma emaphakathi, ukuze ososayensi bakwazi ukuhlola amasistimu okuncibilikisa okusabela afanele ukuze kuqinisekiswe ukuthi ukusabela kwenziwa ngokufanayo nangempumelelo.

Indlela yokuhlanganisa
I-Pyridine kanye ne-piperazine derivatives isetshenziswa kakhulu njengezinto zokuqala, futhi ukusabela kwe-organic classical okufana nokushintshwa kwe-nucleophilic kanye ne-condensation kusetshenziselwa ukwakha izinhlaka zamangqamuzana. Isibonelo, okuphuma ku-pyridine okunokuvikelwa kweqembu okusebenzayo okusebenzayo kuqala kuqala ukusabela kwe-nucleophilic substitution nama-precursors e-piperazine acushiwe ngaphansi kwezimo ze-alkali ukuze enze abaphakathi ababalulekile; Kamuva, ngemva kokuvinjelwa okukhethiwe kanye nezinyathelo ze-hydroxymethylation, umkhiqizo ohlosiwe ungatholakala. Yonke inqubo yokuhlanganisa idinga ukulawula okuqinile kwezinga lokushisa lokusabela, isikhathi sokusabela kanye nesilinganiso sezinto ezibonakalayo, futhi ukuchezuka okuncane kuzothola ukungcola, okuthinta ubumsulwa kanye nesivuno somkhiqizo.

sebenzisa
I-R&D Yezemithi: Isakhiwo sayo esiyingqayizivele samangqamuzana sihlanganisa amaqembu asebenzayo njenge-pyridine ne-piperazine, okubonisa izici zokuba inhlanganisela engaba khona yokuhola izidakamizwa. Lawa maqembu angakwazi ukuxhumana ngokuqondile namaprotheni athile ahlosiwe, njengama-neurotransmitter receptors athile, ezintweni eziphilayo, ehlinzeka ngezifanekiso zesakhiwo ezinoveli zokuthuthukiswa kwemithi emisha yokwelapha izifo zemizwa kanye nezifo zengqondo. Abacwaningi bazolungisa ukwakheka kwayo futhi bahlole umsebenzi wayo ukuze bahlole njalo amandla ayo okwelapha.
I-Organic Building Blocks: Ekuhlanganiseni okuphelele kwama-molecule ezinto eziphilayo eziyinkimbinkimbi, iyibhulokhi yokwakha yekhwalithi ephezulu. Osokhemikhali bangasebenzisa izingosi zabo ezisebenzayo ukuze baxhumanise amaqembu ahlukahlukene asebenzayo ukuze banwebe amaketanga ekhabhoni yamangqamuzana futhi bakhe izinhlelo ezinezindandatho eziningi, bavule imibono yokuhlanganisa kanye nendawo yokusebenza ukuze kudalwe izinhlanganisela eziphilayo ezinezakhiwo zamanoveli nemisebenzi eyingqayizivele.