I-1-Benzyl-1-phenylhydrazine (CAS# 614-31-3)
Isicelo
Isetshenziswa njengama-intermediate emithi.
Ukucaciswa
Ukubukeka uketshezi olucacile.
Faka umbala ophuzi ngokukhanyayo ukuya ku-Brown.
pKa 5.21±0.10(Kubikezelwe).
I-Refractive Index 1.6180-1.6210.
Ukuphepha
Amakhodi Engozi R20/21/22 - Kuyingozi ngokuhogela umoya, ukuthinta isikhumba futhi uma ukugwinyile.
R36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
Incazelo Yezokuphepha S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
I-S36/37/39 - Gqoka izingubo zokuzivikela ezifanele, amagilavu nokuvikela iso/ubuso.
I-Hazard Class IRRITANT.
Ukupakisha & Isitoreji
Ipakishwe ezigubhu ezingu-25kg/50kg. Isimo Sesitoreji Sivalwe ngokomile, Izinga lokushisa Legumbi.
Isingeniso
Njengoba umhlaba wezokwelapha uqhubeka nokuvela, isidingo sabaphakathi bezokwelapha bezinga eliphezulu asikaze sibe sikhulu. Okukodwa okuphakathi okunjalo okuthole ukunakwa okuphawulekayo eminyakeni yamuva i-1-Benzyl-1-phenylhydrazine. Le nhlanganisela ehlukahlukene inezinhlobonhlobo zezicelo futhi isetshenziswa kakhulu ekwenzeni imithi ehlukahlukene kanye nemikhiqizo yemithi. Kulesi sihloko, sizongena sijule emhlabeni we-1-Benzyl-1-phenylhydrazine futhi sihlole izici zayo ezihlukahlukene kanye nokusetshenziswa kwayo.
I-1-Benzyl-1-phenylhydrazine iwuketshezi olucacile olungahlukahluka ngombala ukusuka kophuzi ngokukhanyayo ukuya kunsundu. Inesisindo samangqamuzana angama-211.28 kanye nefomula ye-molecule ye-C14H14N2. I-compound incibilika kakhulu kuzincibilikisi ezihlukahlukene njenge-acetone, i-chloroform, ne-ethanol. Iphinde incibilike kalula emanzini futhi ingafakwa kalula ekwakhiweni kwezidakamizwa okuhlukahlukene.
Isebenzisa:
I-1-Benzyl-1-phenylhydrazine inohlu olubanzi lwezinhlelo zokusebenza embonini yezemithi. Kuyinto ephakathi ebalulekile esetshenziselwa ukuhlanganiswa kwezidakamizwa eziningana ezifana nama-antidepressants, ama-anti-inflammatory agents, nezidakamizwa ze-antihypertensive. Le nhlanganisela iphinde isetshenziswe ekwenzeni imishanguzo yomdlavuza ehlukahlukene kanye nama-antiviral agents. Ukuguquguquka kwe-1-Benzyl-1-phenylhydrazine kuyenza ibe yingxenye ebalulekile ekwakhiweni kohlu olubanzi lwemikhiqizo yemithi.
Abaphakathi Kwezemithi:
Ama-Pharmaceutical intermediate yizinhlanganisela ezisetshenziswa ekuhlanganiseni izithako ezisebenzayo zemithi (APIs). Lezi ziphakathi ziyizingxenye ezibalulekile ekwenziweni kwezidakamizwa futhi zisetshenziswa kakhulu ekwakhiweni kwemikhiqizo yemithi. I-1-Benzyl-1-phenylhydrazine ingenye ephakathi nendawo edlala indima ebalulekile ekwakhekeni kwemithi ehlukahlukene. Izakhiwo zayo ezinemisebenzi eminingi ziyenza ibe yinhlanganisela ebalulekile emhlabeni wemithi.
Ikhwalithi:
Izinga lemithi ephakathi kwemithi libaluleke kakhulu uma kuziwa ekukhiqizeni izidakamizwa eziphephile nezisebenzayo. I-1-Benzyl-1-phenylhydrazine iyinhlanganisela ekhiqizwa ngaphansi kwezinyathelo eziqinile zokulawula ikhwalithi ukuze kuqinisekiswe ukuthi ihlangabezana namazinga aphezulu embonini. Lokhu kuqinisekisa ukuthi imithi ekhiqizwa kusetshenziswa lesi sithako ingeyeqophelo eliphezulu futhi iphephile ukuthi isetshenziswe iziguli.
Sengiphetha, i-1-Benzyl-1-phenylhydrazine iyinhlanganisela ehlukahlukene enezinhlelo eziningi embonini yezemithi. Ikhono layo lokusebenza njengengxenye ephakathi enemisebenzi eminingi liyenza ibe yingxenye ebalulekile ekwakhiweni kwemithi ehlukahlukene kanye nemikhiqizo yezemithi. Izinyathelo eziqinile zokulawula ikhwalithi ezisetshenziswa ekukhiqizeni kwayo ziqinisekisa ukuthi imithi edalwe kusetshenziswa lesi sithako isezingeni eliphezulu futhi iphephile ukuthi isetshenziswe iziguli. Njengoba isidingo semikhiqizo yemithi yekhwalithi ephezulu siqhubeka sikhula, izinhlanganisela ezifana ne-1-Benzyl-1-phenylhydrazine zizoqhubeka zidlala indima ebalulekile embonini yezemithi.
