I-1-Boc-3-piperidone CAS 98977-36-7

Imininingwane Yomkhiqizo

Incazelo Yokuphepha	24/25 - Gwema ukuthintana nesikhumba namehlo.
I-WGK Germany	3
Ikhodi ye-HS	29339900
I-Hazard Class	GCINA KUBANDA

Isingeniso	I-n-tert-butoxycarbonyl-3-piperidone iyisibulala-zinambuzane esibalulekile, iphinde ibe yindawo emaphakathi yemithi kanye nezinye izithasiselo zamakhemikhali. Kunezindlela ezihlukahlukene ezikhona zokwenziwa:(1) kusetshenziswa i-γ-butyrolactone njengento eluhlaza, ngemva kwe-benzylaminolysis, i-hydrolysis, i-esterification, i-condensation ne-ethyl bromoacetate, i-cyclization, ukusabela kwezinyathelo eziyisithupha ze-hydrolytic decarboxylation kukhiqiza i-1-benzyl-3-piperidone. i-hydrochloride, elandelwa yi-debenzylation ye-tert-butoxycarbonyl iqembu elizonikeza i-n-tert-butoxycarbonyl-3-piperidone (US0053565). (2) nge-3-hydroxypyridine njengento eluhlaza, ukusabela nge-benzyl bromide ukukhiqiza usawoti we-quaternary ammonium, i-sodium borohydride ukunciphisa, i-Palladium carbon debenzyl ku-tert-butoxycarbonyl, i-N-tert-butoxycarbonyl-3-piperidone (CN103204801) itholwe nge-low- ukushisa kwe-oxidation ye-dimethyl sulfoxide.
Isicelo	I-n-tert-butoxycarbonyl-3-piperidone iyingxenye emaphakathi ekuhlanganiseni kwezinto eziphilayo kanye nendawo emaphakathi kwezokwelapha, ingasetshenziswa ocwaningweni lwaselabhorethri nenqubo yokuthuthukiswa kanye nenqubo yokuhlanganiswa kwemithi yamakhemikhali, ikakhulukazi esetshenziselwa ukuhlanganiswa kokulawula kwe-stereo kwezinhlanganisela ze-chiral.
Sebenzisa	I-N-tert-butoxycarbonyl-3-piperidone isetshenziselwa ukuhlanganiswa kwe-chiral okulawulwa ngokwemvelo.