1H-Pyrazole-3-carboxylicacid 5-methyl-(CAS# 696-22-0)
| Izimpawu Eziyingozi | Xi - Irritant |
| Amakhodi Engozi | R36/37/38 – Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. |
| Incazelo Yokuphepha | S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. I-S37/39 – Gqoka amagilavu afanelekile kanye nokuvikela iso/ubuso |
Isingeniso
Kuyinhlanganisela yemvelo enefomula yamakhemikhali C5H5N2O2. Ngokuvamile iyikristale engenambala ephuzi ukuya kophuzi.
Inhlanganisela inamaqembu amabili asebenzayo, elinye liyindandatho yepyrazole kanti elinye iqembu elisebenzayo le-carboxylic acid. Inoncibilika okulingene futhi iyancibilika emanzini nasezincibilikisini ezivamile zemvelo. Iqembu le-methyl esakhiweni salo lenza i-hydrophobic.
Njengenhlanganisela ye-heterocyclic, i-5-methyl-inemisebenzi ehlukahlukene yezinto eziphilayo. Isetshenziswa kakhulu ocwaningweni lwezemithi kanye nokuhlanganiswa kwezidakamizwa, ngokuvamile njengento eluhlaza noma emaphakathi. Izicelo eziqondile zihlanganisa ukuhlanganiswa kwe-vitamin B1 analogue, izibulala-zinambuzane, i-plavix inhibitors (inhlanganisela esetshenziselwa ukuvimbela ukukhula kwezitshalo), nokunye okunjalo.
Ukulungiselela, i-5-methyl-ingatholakala ngokuphendula i-athomu ye-nitrogen yeringi ye-pyrazole nge-ejenti ye-methylating (isb. i-methyl iodide). Le ndlela yenziwa ukusabela kwe-N-methylation, indlela evamile ukusabela kwe-nucleophile ehambisanayo ne-N-methyl reagent.
