2-Amino-3-bromo-5-(trifluoromethyl)-pyridine (CAS# 79456-30-7)
| I-Hazard Class | I-IRRITANT |
Isingeniso
I-2-Amino-3-brom-5-(trifluoromethyl)pyridine iyinhlanganisela yemvelo enefomula yamakhemikhali C6H4BrF3N2. Isakhiwo sayo samangqamuzana siqukethe indandatho ye-pyridine ne-athomu ye-bromine, kanye neqembu le-amino kanye neqembu le-trifluoromethyl.
Izici zayo ezingokomzimba zimi kanje:
Ukubukeka: Okuqinile okumhlophe
Izinga lokuncibilika: 82-84°C
Indawo yokubilisa: 238-240°C
Ukuminyana: 1.86g/cm³
Ukunyibilika: Kuncibilika kancane emanzini, kuncibilika kuzincibilikisi eziphilayo njenge-ethanol, i-ether ne-dichloromethane.
Okunye ukusetshenziswa okuyinhloko kwe-2-Amino-3-bromo-5-(trifluoromethyl)pyridine kunjengokumaphakathi kwezemithi. Ingasetshenziselwa ukulungisa izinto eziphilayo ezisebenzayo, njengezidakamizwa, izibulala-zinambuzane kanye nodayi. Ngaphezu kwalokho, ingasetshenziswa futhi njenge-ligand ukubamba iqhaza ekuphenduleni kwamakhemikhali okubangelwa ama-ion ensimbi, njengokusabela kwe-metal catalyzed kanye nokuzwa kwamakhemikhali.
Indlela yokuhlanganisa ye-compound ingafinyelelwa nge-bromopyridine kanye nokusabela kwe-amination. Izinyathelo ezithile zihlanganisa ukuphendula i-bromopyridine nge-ammonia, esikhundleni se-athomu ye-bromine neqembu lama-amino ngaphansi kwezimo eziyisisekelo, bese kwethulwa iqembu le-trifluoromethyl ngaphansi kwesenzo se-reagent ye-trifluoromethylation.
Mayelana nolwazi lokuphepha, i-2-Amino-3-bromo-5-(trifluoromethyl)pyridine iyinhlanganisela yezinto eziphilayo futhi kufanele isetshenziswe ngokunaka izinyathelo zokuzivikela. Ingase ibe nemiphumela ecasulayo futhi eyonakele emehlweni, esikhumbeni nasohlelweni lokuphefumula. Gwema ukuthintana okuqondile ngesikhathi sokusebenza futhi uqinisekise izimo ezinhle zokungenisa umoya. Kunconywa ukuthi ugqoke izinto zokuzivikela ezifana nezibuko zokuzivikela, amagilavu namamaski okuzivikela lapho usebenzisa. Ngesikhathi sokulahlwa, sicela ulandele izidingo zendawo zokulahla imfucuza yamakhemikhali. Ngesikhathi sokugcina, kufanele igcinwe endaweni ephansi yokushisa, eyomile futhi enomoya, ukugwema ukuthintana nama-oxidants nama-acids.
