2-BROMO-3-METHOXYPYRIDINE (CAS# 24100-18-3)
| Izimpawu Eziyingozi | I-Xn - Iyingozi |
| Amakhodi Engozi | I-R22 – Iyingozi uma igwinywe R37/38 – Ukucasula uhlelo lokuphefumula kanye nesikhumba. R41 – Ingozi yokulimala okubi emehlweni |
| Incazelo Yokuphepha | S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. S39 – Gqoka ukuvikela iso / ubuso. |
| I-WGK Germany | 3 |
| Ikhodi ye-HS | 29333990 |
Isingeniso
I-2-bromo-3-methoxypyridine iyinhlanganisela ye-organic enefomula yamakhemikhali i-C6H6BrNO. Okulandelayo yincazelo yemvelo yayo, ukusetshenziswa, ukulungiswa kanye nolwazi lokuphepha:
Imvelo:
-Ukubukeka: uketshezi olungenambala
-Ukunyibilika: Kuncibilika ku-ethanol anhydrous nezincibilikisi ze-Ether
-Indawo yokubilisa: 167-169 ° C
-Ukuminyana: 1.568 g/mL
Sebenzisa:
I-2-bromo-3-methoxypyridine inezinhlelo zokusebenza ezithile emkhakheni wamakhemikhali:
-Njenge-intermediate: ingasetshenziswa ukuhlanganisa amanye ama-organic compounds, njengezidakamizwa, izibulala-zinambuzane kanye nodayi.
-I-Organic synthesis: Ingabamba iqhaza ekuphenduleni okuhlukahlukene okuhlukahlukene, njengokusabela kokushintshwa kwe-electrophilic, ukusabela kwe-condensation, njll.
Indlela:
I-2-bromo-3-methoxypyridine synthesis izindlela ngokuyinhloko yilezi ezilandelayo:
1. Ngokusabela kwe-3-methoxypyridine ne-bromine: i-3-methoxypyridine isabela nge-bromine futhi ishise ngaphansi kwezimo ze-alkali ukuthola umkhiqizo we-2-bromo-3-methoxypyridine.
2. Ngokusabela kwe-pyridine ne-2-Bromo methyl ether: i-pyridine ne-2-Bromo methyl ether reaction, ngaphansi kwezimo ezifanele zokushisa noma ukusebenzisa i-catalyst ukukhiqiza umkhiqizo owufunayo.
Ulwazi Lokuphepha:
Ukuvikeleka kwe-2-bromo-3-methoxypyridine kudinga ukunakwa. Alandelayo amanye amathiphu okuphepha:
-Gwema ukuhogela, ukuthinta isikhumba, noma ukungena emehlweni. Gqoka izinto zokuzivikela ezifanele njengamagilavu, izibuko nezihlangu zobuso ngesikhathi sokusebenzisa.
-Uma uyigcina, kufanele ibekwe endaweni enomoya omuhle, kude nomlilo kanye nama-oxidizing agents.
-Funda ishidi ledatha elifanele lezokuphepha ngokucophelela ngaphambi kokulisebenzisa futhi ulisebenzise ngokuhambisana nezinqubo zokusebenza ezifanele.
