2-Bromopyridine-4-carboxylic acid (CAS# 66572-56-3)
| Izimpawu Eziyingozi | Xi - Irritant |
| Amakhodi Engozi | 36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. |
| Incazelo Yokuphepha | S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. S36 – Gqoka izingubo ezifanele zokuzivikela. I-S36/37 – Gqoka izingubo zokuzivikela ezifanele namagilavu. |
| I-WGK Germany | 3 |
| Ikhodi ye-HS | 29333990 |
| Inothi Lengozi | Iyacasula/Ubande |
| I-Hazard Class | I-IRRITANT |
Isingeniso
I-2-Bromoisoniacin, eyaziwa nangokuthi i-2-bromopyridine-4-carboxylic acid, iyinhlanganisela yezinto eziphilayo. Okulandelayo yisingeniso sezakhiwo, ukusetshenziswa, izindlela zokulungiselela kanye nolwazi lokuphepha lwe-2-bromoisoniacinic acid:
Ikhwalithi:
- Ukubukeka: I-2-Bromoisoniacinic acid iyi-crystalline eqinile emhlophe noma emhlophe.
- Ukunyibilika: Kungancibilika kuzincibilikisi zemvelo ezifana namanzi, i-ethanol, ne-ether.
- Izakhiwo zamakhemikhali: Ingabhekana nokusabela kwe-alkaline hydrolysis ngaphansi kwezimo ze-alkali ukuze ikhiqize izinhlanganisela ze-bromopyridine ezihambisanayo.
Sebenzisa:
- Ingasetshenziswa futhi njengodayi ophakathi ekuhlanganiseni odayi nemibala.
Indlela:
- Indlela evamile yokulungiselela i-2-bromoisoniacinic acid itholakala ngokusabela i-2-picolinic acid ne-thionyl bromide. Xuba i-2-picolinic acid ne-sulfoxide ku-solvent efanele bese wengeza i-acidic catalyst ethile. Khona-ke, i-thionyl bromide yengezwa kancane, futhi ukusabela kwenzeka. Isixazululo sokusabela saphathwa kahle futhi sahlanzwa ukuze kutholwe umkhiqizo we-2-bromoisoniacinic acid onokuhlanzeka okuphezulu.
Ulwazi Lokuphepha: Kuyinto ecasulayo engase ibangele ukucasuka nokungakhululeki lapho uthinta isikhumba, amehlo, noma umgudu wokuphefumula. Izinto zokuzivikela ezifanele ezifana namagilavu, izibuko, nezihlangu zobuso kufanele zigqokwe lapho kusetshenziswa.
- Uma ubamba i-2-bromoisoniacin, gwema ukuhogela uthuli noma umhwamuko wayo. Ngemuva kokwelashwa, izindawo ezingcolile kanye nemishini kufanele ihlanzwe kahle.
- Ukugcinwa ngendlela efanele kwe-2-bromoisoniacin, kufanele igcinwe endaweni eyomile, epholile futhi enomoya omuhle, kude nokushisa kanye nama-oxidants. Gcina ngokuhlukene ezintweni ezivuthayo, ama-asidi nama-ejenti anciphisayo.
- Uma uhogela ngephutha, ukuchayeka, noma ukumunca i-2-bromoisoniacin, funa usizo lwezokwelapha ngokushesha futhi ulethe imiyalelo noma ilebula yomkhiqizo okukhulunywa ngawo.
