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2-(chloromethyl)-5-(trifluoromethyl)-1 3 4-oxadiazole(CAS# 723286-98-4) Isithombe Esifakiwe
  • 2-(chloromethyl)-5-(trifluoromethyl)-1 3 4-oxadiazole(CAS# 723286-98-4) 1

2-(chloromethyl)-5-(trifluoromethyl)-1 3 4-oxadiazole(CAS# 723286-98-4)

Isakhiwo Samakhemikhali:

I-Molecular Formula I-C4H2ClF3N2O
I-Molar Mass 186.52
Ukuminyana 1.555±0.06 g/cm3(Kubikezelwe)
I-Boling Point 55-60 °C(Cindezela: 10 Torr)
I-Flash Point 41.1°C
Ukuncibilika I-Chloroform (Encibilikayo), i-Methanol (Kancane)
I-Vapor Presure 6.44mmHg ku-25°C
Ukubukeka Amafutha
Umbala Okuphuzi Okuphuzi kuya Kuphuzi
pKa -8.11±0.44(Kubikezelwe)
Isimo Sesitoreji Gcina endaweni emnyama, emkhathini ongangeni, Gcina efrijini, ngaphansi kuka -20°C
I-Refractive Index 1.406

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

 

Isingeniso

I-2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole iyinhlanganisela yemvelo enefomula ethi C4H2ClF3N2O.

 

Imvelo:

I-2-(chloromethyl) -5-(trifluoromethyl) -1,3,4-oxadiazole iwuketshezi olungenambala ukuya kokuphuzi okuphaphathekile noma okuqinile okuyicrystalline. Inokuqina kokushisa okuphezulu kanye nokungangeni kwamakhemikhali. Ayincibiliki emanzini ekamelweni lokushisa, incibilika kwezinye izinyibilikisi eziphilayo njenge-ethanol ne-ether. Inhlanganisela ingabonakala ngamasu afana ne-nuclear magnetic resonance kanye ne-mass spectrometry.

 

Sebenzisa:

I-2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole inenani elithile lesicelo emkhakheni wekhemistri. Ivamise ukusetshenziswa njengendawo ephakathi ku-organic synthesis yokuhlanganiswa kwezinye izinhlanganisela. Ngaphezu kwalokho, ibuye isetshenziswe njenge-reagent yocwaningo emkhakheni wezibulala-zinambuzane nemithi.

 

Indlela Yokulungiselela:

I-2-(chloromethyl) -5-(trifluoromethyl) -1,3,4-oxadiazole ingahlanganiswa ngezindlela ezihlukahlukene. Okulandelayo kuyindlela evamile yokulungiselela:

 

1. Engeza i-catalyst (efana ne-triethylamine) ohlelweni lokuncibilikisa lokusabela kwemvelo olunganamanzi.

2. Engeza inani elithile le-methyl 3-chloropropionate ne-methyl trifluoroformate ohlelweni lokuncibilikisa.

3. Ukusabela kwenziwa ekushiseni okufanelekile ngaphansi komkhathi ongasebenzi, futhi ngokuvamile kudingekile ukushisa ingxube yokusabela.

4. Ukuhlunga noma ukucwiliswa ukuze uthole umkhiqizo, ngemva kokuhlanzwa okufanele nokomiswa ukuze uthole umkhiqizo ohlanzekile.

 

Ulwazi Lokuphepha:

I-2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole ngokuvamile iphephile uma isetshenziswa futhi igcinwe ngendlela efanele. Kodwa-ke, njengenhlanganisela yezinto eziphilayo, kungase kubangele ukulimala okuthile empilweni yomuntu kanye nemvelo. Lapho isetshenziswa futhi iphathwa, kufanele ilandele izinqubo zokuphepha ezifanele, futhi igweme ukuthintana ngqo. Imiyalo efanele yokuphepha yenhlanganisela kufanele ifundwe ngokucophelela futhi ilandelwe. Uma kunesidingo, ukusebenza kufanele kwenziwe ngaphansi kokuqondiswa kwabasebenzi abaqeqeshiwe.

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