2-(DIPHENYLMETHYL)-QUINUCLIDIN-3-ONE(CAS#32531-66-1)
2-(DIPHENYLMETHYL)-QUINUCLIDIN-3-ONE, INOMBOLO YECAS 32531-66-1, INEZIMPAHLA EZININGI EZITHAKALISAYO KUMKHEMIRI KANYE NEZINCELO EZIHLOBANE.
Kusukela ekuhlaziyweni kwesakhiwo samakhemikhali, ukwakheka kwawo okuyingqayizivele kwamangqamuzana kuhlanganisa izingxenye zesakhiwo se-diphenyl methyl ne-quinine. Iqembu le-Diphenyl methyl liletha isithiyo esikhulu se-steric kanye nesistimu yokuhlanganisa, ethinta ukugeleza kwefu le-electron ye-molecule, kuyilapho ingxenye ye-quinine cyclic ketone inikeza i-molecule izici ezithile eziqinile neziyisisekelo, futhi lezi ezimbili zakha ngokuhlanganyela isakhiwo samakhemikhali esizinzile kodwa esisebenzayo. Ngokujwayelekile ngesimo se-white crystalline powder, leli fomu eliqinile lisiza ukugcinwa, ukuthuthwa, kanye nokucutshungulwa kokwakheka okulandelayo. Mayelana nokuncibilika, inokuncibilika okuhle kuzinyibilikisi ze-organic ezingezona ze-polar ezifana ne-benzene ne-toluene, okubangelwa indawo engeyona indawo ye-molecule ye-molecule, kuyilapho ingancibiliki kahle kuzincibilikisi ze-polar ezifana namanzi notshwala, kubaluleke kakhulu ekukhetheni i-solvent, ukuhlukaniswa kanye nezinyathelo zokuhlanza ekuhlanganiseni kwamakhemikhali.
Ngokwamandla okusebenza kwezokwelapha, ukwakheka kwawo kuyafana nemithi ethile ekhona ye-psychotropic, okuphakamisa ukuthi ingase isebenze kokuhlosiwe okuhlobene nesistimu yezinzwa emaphakathi. Ucwaningo lwangaphambili lubonise ukuthi kungase kube nomthelela wokulawula ekuthathweni nasekukhululweni kwama-neurotransmitters, futhi kulindeleke ukuthi kusetshenziswe ekwelapheni izifo zengqondo ezifana ne-schizophrenia nokucindezeleka, futhi kuthuthukise izimpawu zeziguli ngokungenelela ekuboniseni izinzwa ezingavamile. Kodwa-ke, okwamanje, iningi labo lisesimweni sokuhlolwa kwamangqamuzana kanye nokuhlolwa kwemodeli yezilwane, futhi kusenendlela ende okufanele ihambe ngaphambi kokuba ibe yizidakamizwa zomtholampilo, futhi kuyadingeka ukuhlola ngokujulile izindlela zabo zemithi, imiphumela emibi enobuthi, i-pharmacokinetics nezinye izici eziningi.
Ngokombono wenqubo ye-synthesis, incike kakhulu emzileni omuhle we-organic synthesis. Ukuqala ngezinto zokusetshenziswa ezilula nezitholakala kalula, i-molecule eqondiwe yakhiwa ngezinyathelo eziyinkimbinkimbi zokusabela ezifana nokuhamba ngebhayisikili, ukushintshwa, nokuhlanganisa. Abacwaningi bazama njalo ama-catalysts amasha kanye nemidiya yokusabela, bathuthukisa izinga lokushisa lokusabela, isikhathi nezinye izimo, futhi balwela ukuthuthukisa ukusebenza kahle kokuhlanganiswa nokunciphisa izindleko, ukuze kuqinisekiswe ukuthi kungenzeka ukulandelwa kocwaningo olunzulu kanye nokukhiqizwa kwezimboni okungaba khona.