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2-Fluoronicotinic acid (CAS# 393-55-5) Isithombe Esifakiwe
  • 2-Fluoronicotinic acid (CAS# 393-55-5) 1

2-Fluoronicotinic acid (CAS# 393-55-5)

Isakhiwo Samakhemikhali:

I-Molecular Formula I-C6H4FNO2
I-Molar Mass 141.1
Ukuminyana 1.419±0.06 g/cm3(Kubikezelwe)
I-Melting Point 161-165°C(lit.)
I-Boling Point 298.7±20.0 °C(Kubikezelwe)
I-Flash Point 122.3°C
I-Vapor Presure 0.00713mmHg ku-25°C
Ukubukeka Impushana emhlophe
Umbala Okumhlophe kuya kokuphuzi
I-BRN 3612
pKa 2.54±0.10(Okubikezelwe)
Isimo Sesitoreji Gcina endaweni emnyama, evalwe endaweni eyomile, Emazingeni Okushisa Egumbi
I-Refractive Index 1.533
I-MDL I-MFCD00040744
Izakhiwo Zomzimba Nezamakhemikhali Impushana emhlophe

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Amakhodi Engozi R36/37/38 – Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
U-R10 – Uyavutha
Incazelo Yokuphepha S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
S36 – Gqoka izingubo ezifanele zokuzivikela.
S16 – Zigcine kude nemithombo yokuthungela.
I-WGK Germany 3
Ikhodi ye-HS 29333990
I-Hazard Class I-IRRITANT

 

Isingeniso

I-2-Fluoronicotinic acid iyinhlanganisela yemvelo enefomula yamakhemikhali ethi C6H4FNO2. Iphuma ku-nicotinic acid (3-oxopyridine-4-carboxylic acid) esakhiweni sayo samakhemikhali, lapho i-athomu eyodwa ye-hydrogen ithathelwa indawo i-athomu ye-fluorine.

 

I-2-Fluoronicotinic acid iyikristale eqinile emhlophe ezinzile ezingeni lokushisa elizungezile. Ine-solubility enhle futhi ingancibilika emanzini. Kuyi-asidi ebuthakathaka eyenza usawoti ngezinsimbi.

 

I-2-Fluoronicotinic acid isetshenziswa kabanzi kweminye imikhakha. Ingasetshenziswa njengengxenye ebalulekile ekuhlanganiseni kwe-organic ukuze kulungiswe ezinye izinhlanganisela noma izidakamizwa. Ngaphezu kwalokho, ingasetshenziswa futhi ku-metal coordination chemistry kanye nokusabela kwe-catalytic.

 

Kunezindlela ezahlukahlukene zokulungiselela i-2-Fluoronicotinic acid. Indlela evamile iwukuba i-fluorination ye-nicotinic acid. Indlela evamile ukusabela kwe-reagent fluorinating, njenge-hydrogen fluoride noma i-trifluoroacetic acid, ene-nicotinic acid ngaphansi kwezimo ezine-acidic ukunikeza i-2-Fluoronicotinic acid.

 

Ukucatshangelwa kokuphepha kuyadingeka lapho uphatha i-2-Fluoronicotinic acid. Kuyinhlanganisela ebolayo futhi kufanele kugqokwe namagilavu ​​okuzivikela afanelekile kanye nezibuko. Gwema ukuhogela uthuli noma umhwamuko wayo ngesikhathi sokusetshenziswa, futhi ugcine indawo yaselabhorethri enomoya omuhle. Lapho uyigcina, idinga ukugcinwa esitsheni esomile, esivalekile, kude nezinto ezivuthayo kanye nama-oxidants.

 

Ngokuvamile, i-2-Fluoronicotinic acid iyinhlanganisela yezinto eziphilayo ezinokuncibilika okuhle nokuzinza. Inezinhlobonhlobo zezinhlelo zokusebenza ku-organic synthesis, ukusebenzisana kwensimbi kanye nokusabela kwe-catalytic, kodwa izinyathelo zokuphepha kufanele zithathwe ngesikhathi sokuphatha nokugcinwa.

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