2-(trifluoromethyl)thiazole-4-carboxylic acid (CAS# 915030-08-9)
| Izimpawu Eziyingozi | I-Xn - Iyingozi |
| Amakhodi Engozi | 22 – Kuyingozi uma kugwinywe |
| I-WGK Germany | 3 |
| I-Hazard Class | I-IRRITANT |
Isingeniso
I-2-(trifluoromethyl) thiazole-4-carboxylic acid iyinhlanganisela ye-organic enefomula yamakhemikhali C5H2F3NO2S. Ubunjalo bayo, ukusetshenziswa, ukwakhiwa kanye nolwazi lokuphepha kuchazwe ngezansi.
Imvelo:
I-2-(trifluoromethyl) thiazole-4-carboxylic acid iyikristale eqinile emhlophe. Ingancibilika kwezinye izinyibilikisi eziphilayo njenge-dimethylsulfamide (DMSO) ne-carbon disulfide (CS2), kodwa ayincibiliki emanzini. Iphuzu layo lokuncibilika lingaba ngu-220-223°C.
Sebenzisa:
I-2-(trifluoromethyl) i-thiazole-4-carboxylic acid iyinhlanganisela esetshenziswa kakhulu ye-organic synthesis. Ingasetshenziselwa ukuhlanganisa ezinye izinhlanganisela ze-bioactive emkhakheni wezokwelapha, njengezidakamizwa nezibulala-zinambuzane. Ngaphezu kwalokho, ingasetshenziswa futhi njengezinto zokwenziwa zokwenziwa zamadayi nezinto ezithatha izithombe.
Indlela:
Ukulungiswa kwe-2-(trifluoromethyl) thiazole-4-carboxylic acid ngokuvamile kutholakala ngokusabela kwe-methyl sulfide ne-cyanomethane. Izinyathelo ezithile zimi kanje: okokuqala, i-2-amino -1, i-3-thiazole isabela nge-trifluoroacetaldehyde ukukhiqiza i-2- (trifluoromethyl) -1, 3-thiazole; bese, i-2-(trifluoromethyl) -1 etholiwe, i-3-thiazole isabela nge-cyanomethane ukuze ikhiqize umkhiqizo ohlosiwe we-2-(trifluoromethyl) thiazole-4-carboxylic acid.
Ulwazi Lokuphepha:
Ubuthi nobungozi be-2-(trifluoromethyl)thiazole-4-carboxylic acid abuhlolisiswanga ngokuphelele. Kodwa-ke, njengekhemikhali, izinqubo zokuphepha ezijwayelekile kufanele zilandelwe, njengokugqoka izinto zokuzivikela ezifanele (njengezibuko, amagilavu namajazi aselabhorethri) nokuphatha endaweni engenawo umoya. Ngemuva kokuchayeka kule nhlanganisela, indawo ethintekile kufanele ihlanzwe ngokushesha ngensipho namanzi. Uma kunesidingo, funa iseluleko sezokwelapha ukuze uthole olunye usizo.
