3-Bromo-2-hydroxy-5-(trifluoromethyl)pyridine (CAS# 76041-73-1)
| Amakhodi Engozi | 25 – Kunobuthi uma kugwinywe |
| Incazelo Yokuphepha | 45 - Uma kwenzeka ingozi noma uzizwa ungaphilile, funa iseluleko sezokwelapha ngokushesha (bonisa ilebula noma nini lapho kungenzeka.) |
| Ikhodi ye-HS | 29333999 |
| I-Hazard Class | I-IRRITANT |
Isingeniso
I-2(1H)-Pyridinone,3-bromo-5-(trifluoromethyl)-(2(1H)-Pyridinone,3-bromo-5-(trifluoromethyl)-) iyinhlanganisela yezinto eziphilayo. Ine-molecular formula ye-C6H3BrF3NO kanye nesisindo se-molecular 218.99g/mol. Okulandelayo yincazelo yemvelo yayo, ukusetshenziswa, ukwakhiwa kanye nolwazi lokuphepha:
Imvelo:
-Ukubukeka: 2 (1H) -Pyridinone,3-bromo-5-(trifluoromethyl) -iqinile, ngokuvamile imhlophe kuya kumakristalu aphuzi aphuzi.
-Indawo yokuncibilika: Indawo yayo yokuncibilika ingu-90-93°C.
-I-Solubility: 2 (1H) -Pyridinone,3-bromo-5-(trifluoromethyl) -ine-solubility ethile kuma-solvents avamile, njenge-ethanol, i-ether ne-chloroform.
Sebenzisa:
-Ucwaningo lwamakhemikhali: 2 (1H) -Pyridinone, 3-bromo-5- (trifluoromethyl) -ingasetshenziswa njenge-reagent noma i-intermediate in organic synthesis. Ivamise ukusetshenziselwa ukwakha uhlaka lwamathambo ezinto eziphilayo eziyinkimbinkimbi ekuphenduleni kwe-metal-catalyzed.
-Ukuthuthukiswa kwezidakamizwa: Ngenxa yesakhiwo sayo esikhethekile kanye nezakhiwo zamakhemikhali, kungase kube nendima ebalulekile ekuthuthukisweni kwezidakamizwa, njengama-anti-cancer agents, ama-antiviral agents, njll.
Indlela Yokulungiselela:
I-2(1H)-Pyridinone,3-bromo-5-(trifluoromethyl)-ingahlanganiswa ngezindlela ezihlukahlukene, okulandelayo kungenye yezindlela ezivamile zokuhlanganisa:
I-2-hydroxyl pyridine isabela ne-magnesium bromide ukuze ikhiqize i-2-hydroxyl -3-bromopyridine. I-3-bromopyridine bese isabela nge-fluoromethyllithium ukunikeza i-2(1H)-Pyridinone,3-bromo-5-(trifluoromethyl)-. I-synthesis ngokuvamile yenziwa ku-solvent ephilayo, njenge-dimethyl sulfoxide, futhi emazingeni okushisa aphansi.
Ulwazi Lokuphepha: Ukuphepha kwe
- I-2(1H)-Pyridinone,3-bromo-5-(trifluoromethyl)-ayikahlolisiswa ngokucacile, ngakho-ke kufanele kuqashelwe lapho kusingathwa futhi kugcinwa. Abasebenzisi bayelulekwa ukuthi bagqoke izinto zokuzivikela ezifanele, njengamagilavu zelabhu nokuvikela amehlo. Gwema ukuhogela uthuli lwayo noma ukuthintana nesikhumba.
-Ngenxa yezakhiwo zayo zamakhemikhali, ingaba yingozi endaweni yamanzi. Sicela uhambisane nezinqubo zokuphepha ezifanele uma usebenzisa, ukuze ugweme ukuphumela emanzini.
-Uma usebenzisa le nhlanganisela, kunconywa ukuthi usebenze ngaphansi kwezimo zaselabhorethri ezinomoya omuhle ukuze ugweme ukuhogela ama-volatiles ayo. Esimeni sokuchitheka noma ukuhogela ngephutha, funa usizo lwezempilo ngokushesha.
