3-CHLORO-2-HYDROXY-5-(TRIFLUOROMETHYL)PYRIDINE (CAS# 76041-71-9)
| Amakhodi Engozi | R25 – Kunobuthi uma ugwinywe R36/37/38 – Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. |
| Incazelo Yokuphepha | S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. I-S36/37 – Gqoka izingubo zokuzivikela ezifanele namagilavu. S45 – Uma kwenzeka ingozi noma uzizwa ungaphilile, funa iseluleko sezokwelapha ngokushesha (bonisa ilebula noma nini lapho kunokwenzeka.) |
| I-WGK Germany | 3 |
| Ikhodi ye-HS | 29333990 |
| I-Hazard Class | I-IRRITANT |
Isingeniso
I-3-Chloro-2-hydroxy-5-(trifluoromethyl)pyridine iyinhlanganisela yezinto eziphilayo. Okulandelayo yisingeniso semvelo yayo, ukusetshenziswa, izindlela zokukhiqiza kanye nolwazi lokuphepha:
1. Imvelo:
- Ukubukeka: 3-Chloro-2-hydroxy-5-(trifluoromethyl)pyridine iqinile elingenambala ukuya kokuphuzi okuphaphathekile.
- Ukunyibilika: Cishe ayincibiliki emanzini, kodwa incibilika kuzincibilikisi eziphilayo njenge-ether, i-methanol ne-methylene chloride.
- Izakhiwo zamakhemikhali: Kuyinhlanganisela ye-alkaline eyenza ukusabela okungathathi hlangothi ngokumelene nama-asidi. Ingasetshenziswa futhi njenge-reagent ye-fluorinating ukwethula amaqembu e-trifluoromethyl kwezinye izinhlanganisela eziphilayo.
2. Ukusetshenziswa:
- I-3-Chloro-2-hydroxy-5-(trifluoromethyl) pyridine ivame ukusetshenziswa ekuphenduleni kwe-organic synthesis njenge-catalyst noma i-reagent. Isibonelo, ingasetshenziselwa ukwakha amabhondi e-carbon-fluorine kanye nokusabela kwe-amination.
- Ingasetshenziswa futhi njengento yokuqala noma emaphakathi ekuhlanganiseni kwezibulala-zinambuzane.
3. Indlela:
- Indlela evame ukusetshenziswa yokulungiselela ukusabela i-pyridine ne-trifluoroformic acid ne-sulfuric acid ukukhiqiza i-3-chloro-2-hydroxy-5-(trifluoromethyl)pyridine.
4. Ulwazi Lokuphepha:
- 3-Chloro-2-hydroxy-5-(trifluoromethyl)pyridine kufanele igwenywe ngesikhathi sokugcinwa futhi isetshenziswe lapho kuthintana nama-oxidants anamandla nezinto ezivuthayo ukugwema umlilo noma ukuqhuma.
- Ingase ibe nomthelela ocasulayo esikhumbeni, emehlweni, nasendleleni yokuphefumula, futhi izinto zokuzivikela ezifanele njengamagilavu, izibuko, nezinto zokuvikela ukuphefumula kufanele zigqokwe lapho usebenza.
- Uma usebenzisa noma uphatha i-compound, kufanele yenziwe endaweni enomoya omuhle futhi ugweme ukuhogela noma ukungenwa ngephutha. Ngemuva kokwelashwa, indawo engcolile kufanele ihlanzwe kahle.
