3-Chloro-5-(trifluoromethyl)pyridine (CAS# 85148-26-1)
| Amakhodi Engozi | R20/21/22 – Kuyingozi ngokuhogela umoya, ukuthintana nesikhumba futhi uma ukugwinyile. R36/37/38 – Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. R25 – Kunobuthi uma ugwinywe |
| Incazelo Yokuphepha | S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. S36/37/39 – Gqoka izingubo zokuzivikela ezifanele, amagilavu kanye nokuvikela iso/ubuso. S36 – Gqoka izingubo ezifanele zokuzivikela. S45 – Uma kwenzeka ingozi noma uzizwa ungaphilile, funa iseluleko sezokwelapha ngokushesha (bonisa ilebula noma nini lapho kunokwenzeka.) |
| Ama-ID e-UN | UN 2811 6.1 / PGIII |
| I-WGK Germany | 3 |
| Inothi Lengozi | Iyacasula |
| I-Hazard Class | I-IRRITANT, IRRITANT-H |
| Iqembu Lokupakisha | III |
Isingeniso
I-3-choro-5-(trifluoromethyl)pyridine iyinhlanganisela yezinto eziphilayo enefomula yamakhemikhali ethi C≡H₂ ClFΛ N. Iwuketshezi olungenambala ukuya kokuphuzi okuphaphathekile olunephunga elimnandi. Okulandelayo incazelo yemvelo, ukusetshenziswa, ukulungiswa kanye nolwazi lokuphepha lwe-3-choro-5-(trifluoromethyl)pyridine:
Imvelo:
-Ukuminyana: 1.578 g/mL
-Indawo yokubilisa: 79-82 ℃
-Indawo yokuncibilika: -52.5 ℃
-I-Solubility: Incibilika kuzincibilikisi eziphilayo njenge-ethanol, i-ether ne-dichloromethane, inyibilika kancane emanzini.
Sebenzisa:
- Njengama-reagents kanye ne-intermediate ku-organic synthesis, esetshenziselwa ukuhlanganiswa kwezibulala-zinambuzane, izidakamizwa nezinye izinhlanganisela eziphilayo.
-Ngokucwaninga emkhakheni wezokwelapha, njengokuhlanganiswa kwezidakamizwa ezilwa nomdlavuza kanye nama-biomarker.
Indlela Yokulungiselela:
I-3-chloro-5-(trifluoromethyl)pyridine ingalungiswa ngezindlela ezimbili ezilandelayo:
1. Ukusebenzisa i-pyridine njengento eluhlaza, ukusabela kwe-chlorination kwenziwa phambi kwe-hydrochloric acid, bese ukusabela kwe-trifluoromethylation kwenziwa phambi kwe-sodium trifluoromethylate.
2. Ukusebenzisa i-3-picolinic acid njengento eluhlaza, ukusabela kwe-chlorination kwenziwa phambi kwe-thionyl chloride, bese ukusabela kwe-trifluoromethylation kwenziwa phambi kwe-trifluoromethyl mercaptan.
Ulwazi Lokuphepha:
- I-3-chloro-5-(trifluoromethyl)pyridine iyacasula futhi ingabangela ukucasuka lapho uthinta isikhumba namehlo. Kuyadingeka ukugqoka izinyathelo zokuzivikela ezifanele lapho usebenzisa, njengokugqoka izibuko zokuzivikela, amagilavu nezingubo zokuzivikela.
-Gwema ukuhogela umhwamuko wawo futhi uqinisekise ukuthi ukuhlinzwa kwenziwa endaweni enomoya omuhle.
-Lapho uyigcina, yigcine esitsheni esivalekile, kude nomlilo kanye nama-oxidizing agents.
-Lapho ulahla imfucuza, yiphathe futhi uyilahle ngokuhambisana nemithetho yendawo.
-Sicela uhlole Ishidi Ledatha Yezokuphepha elifanele (SDS) ukuze uthole ulwazi oluningiliziwe lokuphepha.
