4-[(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile（CAS# 189956-45-4)

I-Molecular Formula	I-C11H8N4O
I-Molar Mass	212.21
Ukuminyana	1.31±0.1 g/cm3(Kubikezelwe)
I-Melting Point	> 300°C
I-Boling Point	399.7°C ku-760 mmHg
I-Flash Point	195.6°C
Ukuncibilika	I-DMSO (Kancane), i-Methanol (Kancane)
I-Vapor Presure	0-0Pa ku-20-25℃
Ukubukeka	Okuqinile
Umbala	U-Pale Brown kuya ku-Brown
pKa	8.66±0.40(Okubikezelwe)
Isimo Sesitoreji	2-8°C
I-Refractive Index	1.67

Imininingwane Yomkhiqizo

I-LogP	0.9 ku-pH6.6
sebenzisa	I-4--[(4-hydroxy-2-pyrimidinyl) amino] i-benzonitrile ingasetshenziswa njengendawo ephakathi ku-organic synthesis kanye ne-intermediate yemithi, futhi ingasetshenziswa kunqubo ye-laboratory ye-Organic synthesis kanye nenqubo yokucwaninga amakhemikhali nemithi kanye nentuthuko.
ukulungiselela	nesisindo esingu-2-(methylthio) pyrimidine -4(3H)-one (3g,21mmol) kanye ne-4-aminobenzonitrile (2.99g,25mmol) eflaskini eyindilinga eyindilinga engu-50mL, evikelwe i-nitrogen, ishisiswe kancane ibe ngu-180 ℃, futhi isabela ngo-8. amahora. Ngemuva kokuthi ukusabela sekupholile, i-20mL ye-acetonitrile yengezwa ukuze iphathwe nge-ultrasonic, ukuhlunga, ikhekhe lokuhlunga ligezwa nge-acetonitrile, akukho nsalela ye-4-aminobenzonitrile etholwa yi-TLC, futhi okuqinile okuphuzi okukhanyayo okutholwe ngokomisa ikhekhe lokuhlunga kungu-4-( (4-oxo -1, 6-dihydropyrimidine -2-yl) amino) i-benzonitrile ene- isivuno esingu-73.6%.