4-Chloro-2-fluorobenzoic acid (CAS# 446-30-0)
Ubungozi Nokuphepha
| Amakhodi Engozi | R36/37/38 – Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. I-R22 – Iyingozi uma igwinywe |
| Incazelo Yokuphepha | S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. S36 – Gqoka izingubo ezifanele zokuzivikela. I-S37/39 – Gqoka amagilavu afanelekile kanye nokuvikela iso/ubuso |
| I-WGK Germany | 3 |
| Ikhodi ye-HS | 29163990 |
| I-Hazard Class | I-IRRITANT |
446-30-0 - Ulwazi Lwereferensi
| Isicelo | I-4-chloro-2-fluoro-benzoic acid iyisithako esibalulekile ku-organic synthesis kanye nemithi, isetshenziswa kakhulu kuma-fungicides, ama-ATX inhibitors, ama-NHE3 inhibitors kanye nama-NMDA receptor antagonists. |
| Izakhiwo zamakhemikhali | amakristalu amhlophe noma amhlophe. Iphoyinti lokuncibilika 206-210 °c. |
| Isicelo | esetshenziswa njengesibulala-zinambuzane kanye nemithi Lesisemkhatsini |
Isingeniso esifushane
I-4-Chloro-2-fluorobenzoic acid iyinhlanganisela ephilayo. Okulandelayo yisingeniso sezakhiwo zayo, ukusetshenziswa kwayo, izindlela zokukhiqiza kanye nolwazi lokuphepha:
Ikhwalithi:
I-4-Chloro-2-fluorobenzoic acid iyikristalu eqinile, ngokuvamile engenambala noma amakristalu aphuzi. Ayiguquguquki ezingeni lokushisa legumbi. Inephunga elimnandi futhi ingancibilika kuzincibilikisi zemvelo ezifana ne-methanol, i-ethanol, i-methylene chloride, njll.
Sebenzisa:
I-4-Chloro-2-fluorobenzoic acid inezinhlobonhlobo zezicelo embonini yamakhemikhali. Ivame ukusetshenziswa njengento yokuqala noma emaphakathi ku-organic synthesis. Ingasetshenziswa futhi njengesitoko sokuphakelayo sama-catalyst nezinto zikagesi.
Indlela:
I-4-Chloro-2-fluorobenzoic acid ingatholakala ngokuxutshwa kwe-p-fluorobenzoic acid. Ngokuvamile, i-hydrogen chloride noma i-chlorous acid ingasabela nge-thionyl chloride noma i-sulfinyl chloride ngaphansi kwezimo ezine-acidic, kulandelwa ukusabela nge-hydrogen fluoride ukuze kutholwe i-4-chloro-2-fluorobenzoic acid.
Ulwazi Lokuphepha:
Lezi zinyathelo zokuphepha ezilandelayo kufanele zithathwe lapho uphatha i-4-chloro-2-fluorobenzoic acid: gwema ukuthintana nesikhumba namehlo, futhi unake izinyathelo zokuzivikela ezinjengokugqoka izibuko zokuzivikela namagilavu. Kufanele wenziwe endaweni enomoya omuhle ukuvimbela ukuhogela noma ukugwinya. Gwema ukuthinta izinto ezivuthayo futhi ugweme amalangabi avulekile noma amazinga okushisa aphezulu. Kumelwe ivalwe ngokuqinile lapho isetshenziswa noma igcinwe futhi kude nama-asidi, izisekelo, nama-oxidants. Uma kwenzeka kuvuza, izinyathelo eziphuthumayo ezifanele kufanele zithathwe, njengokumunca uketshezi nge-desiccant noma ukulihlanza nge-adsorbent yamakhemikhali efanelekile.
