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I-4-Hydroxybenzyl alcohol(CAS#623-05-2) Isithombe Esifakiwe
  • I-4-Hydroxybenzyl alcohol(CAS#623-05-2) 1

I-4-Hydroxybenzyl alcohol(CAS#623-05-2)

Isakhiwo Samakhemikhali:

I-Molecular Formula C7H8O2
I-Molar Mass 124.14
Ukuminyana 1.1006 (isilinganiso esinzima)
I-Melting Point 114-122°C(lit.)
I-Boling Point 251-253°C
I-Flash Point 251-253°C
Inombolo ye-JECFA 955
Ukuncibilika kwamanzi Incibilika emanzini (6.7 mg/ml ku-20°C), i-dioxane (100 mg/ml), i-1N NaOH (50 mg/ml), i-DMSO, ne-methanol.
Ukuncibilika I-Soluble ku-methanol, i-ethanol, i-DMSO nezinye izincibilikisi eziphilayo.
I-Vapor Presure 0.0104mmHg ku-25°C
Ukubukeka Pink, beige (crystalline powder)
Umbala Pink kuya beige
I-BRN 1858967
pKa pK1:9.82 (25°C)
Isimo Sesitoreji Gcina ngaphansi kuka +30°C.
Kuyazwela Izwela Ukukhanya/Izwela Umoya
I-Refractive Index 1.5035 (isilinganiso)
I-MDL Idatha ye-MFCD00004658
Izakhiwo Zomzimba Nezamakhemikhali indawo yokuncibilika 110-112°C
Sebenzisa Isetshenziswa njengendawo emaphakathi ku-organic synthesis
Isifundo se-in vitro I-4-Hydroxybenzyl alcohol ivimbela ukwanda kwamaseli e-eEND2 futhi icindezela ukufuduka kwamaseli e-eEND2, okuhambisana nokuvinjwa kokuhlelwa kabusha kwe-actin filament. I-4-Hydroxybenzyl alcohol idala ukufa kwe-apoptotic yamaseli wesimila.
Isifundo se-vivo I-4-Hydroxybenzyl alcohol inomsebenzi we-antiangiogenic, anti-inflammatory kanye ne-anti-nociceptive ngokunokwenzeka ngomsebenzi wayo olawula phansi ekukhiqizeni AKUKHO. I-4-Hydroxybenzyl alcohol (200 mg/kg) ivimbela kahle ukukhula kanye ne-angiogenesis yezimila ezikhulayo. I-4-Hydroxybenzyl alcohol ithuthukisa ukulimala kwe-ischemic okudalwe ukugxila kwesikhashana kwe-cerebral ischemia kumagundane, futhi lo mphumela we-neuroprotective ungase uhlotshaniswe ngokwengxenye nokunciphisa indlela ye-apoptosis.

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Izimpawu Eziyingozi Xi - Irritant
Amakhodi Engozi R36 – Ukucasuka emehlweni
R36/37/38 – Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
Incazelo Yokuphepha S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
I-S24/25 - Gwema ukuthintana nesikhumba namehlo.
S36 – Gqoka izingubo ezifanele zokuzivikela.
I-WGK Germany 3
I-RTECS I-DA4796800
AMAKHODI E-FLUKA BRAND F 8-9-23
Ikhodi ye-HS 29072900
Inothi Lengozi Iyacasula/Hlala Ubanda/Uzwela Umoya/Uzwela Ukukhanya

 

Isingeniso

I-Hydroxybenzyl alcohol iyinhlanganisela yemvelo enesakhiwo samakhemikhali se-C6H6O2, esivame ukwaziwa nge-phenol methanol. Nazi ezinye izakhiwo ezivamile, ukusetshenziswa, izindlela zokulungiselela kanye nolwazi lokuphepha mayelana ne-hydroxybenzyl alcohol:

 

Ikhwalithi:

Ukubukeka: Uketshezi oluqinile oluqinile noma olumafinyila alunambala ukuya kokuphuzi.

I-Solubility: Incibilika kuzincibilikisi zemvelo ezifana namanzi, utshwala ne-ether.

 

Sebenzisa:

Izivimbelakuvunda: Inezinto ezilwa namagciwane kanye ne-antiseptic, kanti i-hydroxybenzyl alcohol nayo isetshenziswa njengesivikelo sokhuni.

 

Indlela:

I-Hydroxybenzyl alcohol ngokuvamile ikhiqizwa ukusabela kwe-para-hydroxybenzaldehyde nge-methanol. Ukusabela kungenziwa i-ejenti ene-oxidizing, njenge-catalyst Cu(II.) noma i-ferric chloride(III.). Ukusabela ngokuvamile kwenziwa ekamelweni lokushisa.

 

Ulwazi Lokuphepha:

I-Hydroxybenzyl alcohol inobuthi obuphansi, kodwa kusadingeka ukunakekelwa ukuze kuphathwe ngokuphepha.

Uma uthinta isikhumba, hlambulula ngokushesha ngamanzi amaningi. Uma ugwinyile, funa usizo lwezokwelapha ngokushesha.

Ukuthintana nama-oxidants, ama-acids, nama-phenol kufanele kugwenywe ngesikhathi sokuphatha nokugcinwa ukuze kuvinjelwe ukusabela okuyingozi.

Lapho usebenzisa noma uyigcina, kufanele igcinwe kude namalangabi avulekile noma amazinga okushisa aphezulu ukuvimbela umlilo.

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