5-amino-2-fluorobenzoic acid (CAS# 56741-33-4)
| Amakhodi Engozi | R36/37/38 – Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. I-R22 – Iyingozi uma igwinywe |
| Incazelo Yokuphepha | S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. S36 – Gqoka izingubo ezifanele zokuzivikela. S37 – Gqoka amagilavu afanelekile. |
| Ikhodi ye-HS | 29163990 |
| Inothi Lengozi | Iyacasula |
Isingeniso
I-5-amino-2-fluorobenzoic acid iyinhlanganisela ye-organic enefomula yamakhemikhali C7H6FNO2. Iqinile ngokucwebezelayo emhlophe, ezinzile ezingeni lokushisa legumbi. Okulandelayo yincazelo yemvelo yayo, ukusetshenziswa, ukulungiswa kanye nolwazi lokuphepha:
Imvelo:
1. Ukubukeka: I-5-amino-2-fluorobenzoic acid iyikristale eqinile emhlophe.
2. Ukunyibilika: Ine-solubility ephansi emanzini futhi ingancibilika kancane kuzincibilikisi zemvelo njenge-ethanol ne-ketone.
3. Ukuzinza kwe-thermal: Inokuqina okuhle kokushisa futhi akulula ukubola ngesikhathi sokushisa.
Sebenzisa:
I-5-amino-2-fluorobenzoic acid iyingxenye ebalulekile ye-organic synthesis futhi ivame ukusetshenziswa ezimbonini zemithi nezodayi.
1. Ukusetshenziswa kwemithi: Ingasetshenziswa ukwenza ezinye izidakamizwa, njenge-clozapine.
2. Ukusetshenziswa kodayi: Kungasetshenziswa njengesandulela sikadayi ukuze kuhlanganiswe abanye odayi abanemibala.
Indlela Yokulungiselela:
Izindlela zokulungiselela i-5-amino-2-fluorobenzoic acid ikakhulukazi zihlanganisa okulandelayo:
1. Ukusabela kwe-Fluorination: I-2-fluorobenzoic acid ne-ammonia zisabela kanye ne-catalyst ukuthola i-5-amino-2-fluorobenzoic acid.
2. Ukusabela kwe-diazo: okokuqala lungisa inhlanganisela ye-diazo ye-2-fluorobenzoic acid, bese usabela nge-ammonia ukukhiqiza i-5-amino-2-fluorobenzoic acid.
Ulwazi Lokuphepha:
Ulwazi lokuphepha ku-5-amino-2-fluorobenzoic acid ludinga ucwaningo olwengeziwe nokuqinisekiswa kokuhlolwa. Lapho isetshenziswa kufanele inake amaphuzu alandelayo:
1. Gwema ukuthintana: gwema ukuthinta isikhumba, amehlo kanye nomgudu wokuphefumula. Hlanza ngamanzi ahlanzekile ngokushesha ngemva kokuxhumana.
2. Qaphela Isitoreji: Gcina endaweni eyomile, epholile, kude nomlilo nezinto ezivuthayo.
3. inothi lokusebenza: ekusetshenzisweni kwenqubo kufanele agqoke amagilavu okuzivikela, izibuko kanye nemaski, ukuqinisekisa umoya omuhle.
