5-bromo-2-pyridinecarboxylic acid ethyl ester (CAS# 77199-09-8)

Isingeniso

I-Ethyl 5-bromo-2-pyrimidincarboxylate iyinhlanganisela yezinto eziphilayo. Okulandelayo ulwazi mayelana nezakhiwo, ukusetshenziswa, izindlela zokulungiselela nokuphepha kwe-compound:

Ikhwalithi:

- Ukubukeka: I-Ethyl 5-bromo-2-pyrimidincarboxylate iwuketshezi olungenambala ukuya kokuphuzi okuphaphathekile.

- I-Solubility: Ingancibilika kuzincibilikisi zemvelo njenge-ethanol ne-methylene chloride, kodwa ayincibiliki emanzini.

Sebenzisa:

- I-Ethyl 5-bromo-2-pyrimidincarboxylic acid ivame ukusetshenziswa njengento ebalulekile emaphakathi ekuhlanganiseni kwe-organic.

- Ingasetshenziswa futhi njenge-reagent yokuhlaziya ezindaweni zocwaningo.

Indlela:

- Ukuhlanganiswa kwe-ethyl 5-bromo-2-pyrimidincarboxylic acid kungatholakala ngokufaka i-esterification ye-bromobenzoic acid kwindandatho ye-pyrimidine.

- Kule nqubo, i-p-bromobenzoic acid ne-isopropyl carbonate ziqala ukusabela ukukhiqiza isopropyl p-bromobenzoate, bese ngokungeza i-pyrimidine eyeqile, ukushisa ezingeni lokushisa elifanele futhi kusabela isikhathi esithile, i-5-bromo-2- yokugcina yokugcina I-pyrimidincarboxylate ethyl ester iyatholakala.

- Naka izinga lokushisa lokusabela, isikhathi sokusabela, kanye nenani elikhulu lama-reactants ngesikhathi sokulungiselela ukuthola umkhiqizo onesivuno esikhulu nobumsulwa.

Ulwazi Lokuphepha:

- I-Ethyl 5-bromo-2-pyrimidincarboxylate iyinhlanganisela yezinto eziphilayo futhi iyasha.

- Landela izinqubo zokuphepha zaselabhorethri futhi ugqoke izinto zokuzivikela ezifanele njengamagilavu ​​nezibuko lapho usebenzisa noma uphatha.

- Gwema ukuthinta isikhumba, amehlo, kanye nokuhogela.

- Uma uthintana ngephutha, geza indawo ethintekile ngamanzi amaningi futhi ufune usizo lwezokwelapha.