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3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid ethyl ester (CAS#128073-16-5) Isithombe Esifakiwe
  • 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid ethyl ester (CAS#128073-16-5) 1

3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid ethyl ester (CAS#128073-16-5)

Isakhiwo Samakhemikhali:

I-Molecular Formula I-C9H7ClF3NO2
I-Molar Mass 253.61
Ukuminyana 1.389±0.06 g/cm3(Kubikezelwe)
I-Boling Point 64-66℃/0.008mm
I-Flash Point 121.2°C
I-Vapor Presure 0.0047mmHg ku-25°C
Ukubukeka uketshezi olucacile
Umbala Okungenambala kuya kokuwolintshi okukhanyayo ukuya kokuphuzi
pKa -3.19±0.10(Kubikezelwe)
Isimo Sesitoreji ngaphansi kwegesi ye-inert (nitrogen noma i-Argon) ku-2-8°C
I-Refractive Index 1.4590 ukuze 1.4630

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Izimpawu Eziyingozi Xi - Irritant

 

Isingeniso

I-Ethyl 3-chloro-5-trifluoromethylpyridin-2-carboxylate, eyaziwa nangokuthi i-Fmoc-Cl. Okulandelayo yisingeniso sezakhiwo zayo, ukusetshenziswa kwayo, izindlela zokukhiqiza kanye nolwazi lokuphepha:

 

Ikhwalithi:

Ukubukeka: Uketshezi olungenambala.

I-Solubility: Incibilika kuma-organic solvents.

 

Sebenzisa:

I-FMOC-CL iyiqembu elibalulekile elivikelayo ku-organic synthesis. Ingasabela nge-oxyamine ukuze ikhiqize okuphuma kokunye okuvikelwe kwe-Fmoc kwama-amino acid noma ama-peptide ukuze kuhlanganiswe isigaba esiqinile.

Ingasetshenziswa futhi ekuvikeleni amakhemikhali e-radical of other chemical synthesis reactions.

 

Indlela:

Ukuhlanganiswa kwe-FMOC-CL kuvame ukubandakanya lezi zinyathelo ezilandelayo:

I-hydrochloride ye-3-chloro-5-trifluoromethylpyridine-2-carboxylic acid yalungiswa kuqala.

IHydrochloride isabela ngesisekelo (isb, i-triethylamine) ukuze yakhe i-Fmoc-Cl.

 

Ulwazi Lokuphepha:

I-FMOC-CL ingase icasule isikhumba, amehlo, nolwelwesi lwamafinyila, ngakho gqoka amagilavu ​​okuzivikela kanye nezibuko lapho uyisebenzisa.

Gwema ukuhogela umoya nokuthintana ngesikhathi sokusebenza, futhi uyigcine ingena umoya.

Uma uhogela umoya noma uthinta isikhumba, hlambulula ngokushesha ngamanzi ahlanzekile futhi ufune usizo lwezokwelapha ngokushesha.

Lapho igcinwa, kufanele ivalwe futhi igcinwe kude nokushisa nomlilo.

Njalo qaphela ukuphepha futhi ulandele izinqubo ezifanele zokusebenza zokuphepha lapho usebenzisa noma uphatha noma yiziphi izinto zamakhemikhali.

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