6-Bromo-7-chloro-3H-imidazo[4 5-b]pyridine（CAS# 83472-62-2)

Isingeniso

I-3-Methyl-2,4-dichlorobenzoic acid iyinhlanganisela yezinto eziphilayo. Okulandelayo yisingeniso sobunjalo bayo, ukusetshenziswa, indlela yokulungiselela kanye nolwazi lokuphepha:

Ikhwalithi:

- Ukubukeka: Okuqinile kwecrystalline engenambala

- Ukunyibilika: kuncibilika kuzincibilikisi eziphilayo njenge-ethanol, i-ether ne-methylene chloride, engancibiliki emanzini.

Sebenzisa:

- Izibulala-zinambuzane: I-3-methyl-2,4-dichlorobenzoic acid iyisibulala-zinambuzane esibanzi esingasetshenziswa ukulawula ukukhula kokhula oluhlukahlukene, njengotshani obuzungeze izitshalo ezifana ne-kale, legumes, kanye nommbila.

Indlela:

I-3-Methyl-2,4-dichlorobenzoic acid ingalungiswa nge-chlorination ye-p-methylanise ether (3-methylanisole). Indlela ethile yokulungiselela ingabandakanya lezi zinyathelo ezilandelayo:

Chaza i-3-methylanisole ku-anhydrous hydrochloric acid.

I-sodium chlorite (NaClO) noma i-potassium chlorite (KClO) yengezwe njengemithombo ye-chlorine.

Ingxube yokusabela inyakaziswa emazingeni okushisa aphansi, ngokuvamile phakathi kuka-0-5 °C.

Ngemva kokuqedwa kokusabela, ingxube iyahlungwa noma ikhishwe ukuze kutholwe umkhiqizo we-3-methyl-2,4-dichlorobenzoic acid.

Ulwazi Lokuphepha:

- I-3-Methyl-2,4-dichlorobenzoic acid ingase ibangele ukulimala emvelweni, futhi kufanele kuqashelwe ukulawula ukusetshenziswa nokulahlwa kwemfucuza.

- Ukuthintana ngqo nomuthi kungase kucasule isikhumba, amehlo, nohlelo lokuphefumula, futhi ukuthintana ngqo kufanele kugwenywe.

- Gqoka okokuvikela okufanele njengamagilavu, izibuko, namamaski lapho usetshenziswa.

- Kufanele kuqashelwe ukuvimbela ukuxubana namanye amakhemikhali ngesikhathi sokugcinwa nokuphathwa, futhi ugweme ukuthungela kanye nokushisa okuphezulu.

- Sicela ufunde futhi ulandele amashidi edatha okuphepha afanele nemihlahlandlela yokusebenza ngaphambi kokuwasebenzisa. …