6-bromopyridine-2-carboxylic acid ethyl ester (CAS# 21190-88-5)
| Izimpawu Eziyingozi | Xi - Irritant |
| Amakhodi Engozi | 36 - Ukucasula emehlweni |
| Incazelo Yokuphepha | 26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. |
Isingeniso
i-acid ethyl ester iyinhlanganisela yezinto eziphilayo enefomula yamakhemikhali ethi C8H8BrNO2. Iwuketshezi olungenambala olunephunga elikhethekile. I-compound iyancibilika kuma-organic solvents njenge-ethanol, i-dimethylformamide ne-benzene, futhi ayincibiliki emanzini.
i-acid ethyl ester inezinhlobonhlobo zezicelo ku-organic synthesis. Ingasetshenziswa njengendawo emaphakathi yemithi yokuhlanganiswa kohlu olubanzi lwezidakamizwa nama-molecule e-bioactive. Ngaphezu kwalokho, ingasetshenziswa futhi ekuphenduleni kwe-Gormperman kanye ne-palladium-catalyzed cross-coupling reactions ku-organic synthesis.
Kunezindlela ezimbili ezijwayelekile ze-acid ethyl ester:
1. Itholakala ngokusabela kwe-6-bromopyridine ne-chloroacetate, bese i-hydrolyzed nge-alkali ngemva kokusabela.
2. Nge-6-bromopyridine ne-chloroacetic acid ester reaction, i-acid chloride, bese isabela ngotshwala ukuze uthole umkhiqizo.
Izinyathelo zokuphepha ziyadingeka lapho usebenzisa futhi ugcina i-acid ethyl ester. Iwuketshezi oluvutha umlilo futhi kufanele igcinwe endaweni epholile, enomoya omuhle, kude nomlilo kanye namazinga okushisa aphezulu. Izinto ezisetshenziswayo zokuvikela ezifanele, njengamagilavu elebhu nezibuko, kufanele zigqokwe ngesikhathi sokusebenza. Uma ukugwinya noma ukuthinta isikhumba noma amehlo, geza ngokushesha ngamanzi amaningi futhi ufune usizo lwezokwelapha.
