I-8-bromo-1 6-naphthyridin-5(6H)-one (CAS# 155057-97-9)
I-8-bromo-1, 6-naphythyridin-5 (6h)-enye iyinhlanganisela yemvelo enefomula ye-molecular C13H8BrNO, okuwumpuphu oqinile.
Izakhiwo zalesi sakhiwo yilezi:
1. Ukubukeka: 8-bromo-1, 6-naphythyridin-5 (6h) -enye i-crystal powder emhlophe noma ephuzi ekhanyayo.
2. Iphuzu Elincibilikayo: linendawo ephezulu yokuncibilika, cishe 206-210 ℃.
3. Ukunyibilika: Inokuncibilika okuhle kwezinye izinyibilikisi zemvelo (njenge-chloroform, i-acetone ne-dimethyl sulfoxide).
Inezicelo eziningi elabhorethri nasembonini:
1. Ama-Chemical reagents: angasetshenziswa njengama-reagents ekuphenduleni kwe-organic synthesis, njengezicelo ekuhlanganiseni kwezidakamizwa nezibulala-zinambuzane.
2. Impahla ye-photosensitive: ngenxa yemvelo ekhethekile yesakhiwo sayo samangqamuzana, ingasetshenziselwa ukulungiswa kwezinto ezithatha izithombe.
3. I-Organic synthesis intermediates: ingasetshenziswa njengeziphakathi zokuhlanganiswa kwezinye izinhlanganisela.
Mayelana nendlela yokulungiselela, i-8-bromo-1,6-naphthyridin-5(6h)-enye ingalungiswa ngezinyathelo ezilandelayo:
1. Okokuqala, i-1,6-naphthoketone isabela nge-hydrogen bromide. Izimo zokusabela zingenziwa ngokufudumeza phambi kwe-acetic acid.
2. Umkhiqizo wokusabela yi-8-bromo -1,6-naphthoketone, ukuqhubeka nokucutshungulwa:
a. I-8-bromo -1,6-naphthoketone isabela nge-pyridine ngaphansi kwe-acid catalysis.
B. Izimo zokusabela ukusabela kwe-Reflux, ngokuvamile ku-acetic acid.
c. Umkhiqizo otholwe ngokusabela yi-8-bromo-1,6-naphthyridin-5(6h)-one.
Mayelana nolwazi lokuphepha, i-8-bromo-1,6-naphthyridin-5(6h)-one iyinhlanganisela yezinto eziphilayo, ngakho-ke izinyathelo ezifanele zokuphepha kufanele zithathwe:
1. Gwema ukuthintana nesikhumba namehlo, njengokuthintana, kufanele ugeze ngokushesha ngamanzi amaningi.
2. Ukusetshenziswa kufanele kwenziwe endaweni engenawo umoya ukuze kugwenywe ukuhogela uthuli lwayo.
3. Kufanele igcinwe kude nomlilo kanye ne-oxidant.
4. Landela izinqubo ezifanele zaselabhorethri kanye nezinyathelo zokuzivikela.
