I-Benzeneacetonitrile (CAS#140-29-4)

I-Benzeneacetonitrile (CAS#140-29-4)

I-Benzeneacetonitrile, inombolo ye-CAS 140-29-4, ihlukile ezicini eziningi zamakhemikhali.
Kusukela esakhiweni samakhemikhali, yakhiwe indandatho ye-benzene exhunywe eqenjini le-acetonitrile. Indandatho ye-benzene inohlelo olukhulu lokuhlanganisa lwebhondi engu-π, olunikeza i-molecule ukuzinza nokusabalalisa kwamafu e-electron eyingqayizivele, okuyenza ibe nokunuka okuthile. Iqembu le-acetonitrile lethula i-polarity eqinile kanye nokusebenza kabusha kweqembu le-cyano, okwenza i-molecule yonke ingagcini nje ngokuba nokungabi nalutho okuhlobene kanye ne-hydrophobicity elethwa indandatho ye-benzene, kodwa futhi inikeze amathuba acebile e-organic synthesis ngoba iqembu le-cyano lingabamba iqhaza ezinhlobonhlobo. ukusabela kwe-nucleophilic kanye ne-electrophilic. Ivamise ukubonakala njengoketshezi oluphuzi olukhanyayo olungenambala ukuya kokukhanyayo, futhi lolu ketshezi lukulungele ukudluliswa nokuhlanzwa ngokusebenzisa imisebenzi evamile efana nokuhlukaniswa koketshezi kanye nokuhluzwa kwezimo endaweni yaselabhorethri kanye nezimo ze-industrial synthesis. Ngokuvumelana ne-solubility, ingancibilika kangcono kuzincibilikisi zemvelo, njenge-ether, i-chloroform nezinye izincibilikisi ze-polar ezingezona ze-polar noma ezibuthakathaka, kuyilapho ukuncibilika kwamanzi kubi, okuhlobene eduze ne-molecular polarity, futhi kuphinde kunqume ukukhetha kwayo ukusetshenziswa. ezinhlelweni ezahlukene zokusabela.
Iyingxenye ebalulekile yezinhlelo zokusebenza ze-organic synthesis. Ngokusekelwe ezintweni zabo zesakhiwo, ukusabela okuhlukahlukene kwamakhemikhali kungenzeka ukuze kwakhiwe izinhlanganisela eziyinkimbinkimbi. Isibonelo, ngokusebenzisa ukusabela kwe-hydrolysis ye-cyanogroup, i-phenylacetic acid ingalungiswa, esetshenziswa emkhakheni wezokwelapha ukuze kuhlanganiswe izidakamizwa ezihlukahlukene, njengokuguqulwa kwe-side chain of antibiotics penicillin; Embonini yezinongo, iwukhiye osetshenziswa ekulungiseni izinongo zezimbali ezinjengama roses kanye nomnduze wasesigodini. Ngaphezu kwalokho, ukusabela kokunciphisa kwe-cyano kungabuye kusetshenziselwe ukuyiguqula ibe yinhlanganisela ye-benzylamine, futhi okuphuma ku-benzylamine kusetshenziswe kabanzi emkhakheni wezibulala-zinambuzane nodayi, futhi kusetshenziselwa ukuthuthukisa izibulala-zinambuzane ezintsha ezisebenza kahle kakhulu, odayi abanemibala egqamile kanye nokuphakama okuphezulu. ukushesha.
Mayelana nendlela yokulungiselela, i-acetophenone ivame ukusetshenziswa njengezinto ezingavuthiwe embonini, futhi ilungiswa ukusabela okuzinyathelo ezimbili kwe-oxime kanye nokuphelelwa amandla kwamanzi. Okokuqala, i-acetophenone isabela nge-hydroxylamine ukuze yakhe i-acetophenone oxime, eguqulwa ibe yi-Benzeneacetonitrile ngaphansi kwesenzo se-dehydrator, futhi kule nqubo, abacwaningi baqhubeka nokwandisa izimo zokusabela, okuhlanganisa ukulungisa izinga lokushisa lokuphendula nokulawula inani le-dehydrator, ngakho-ke. mayelana nokwenza ngcono isivuno, ukunciphisa izindleko, nokuqinisekisa isidingo sokukhiqiza okukhulu. Ngokusungulwa kobuchwepheshe be-organic synthesis, ukwenziwa kahle komzila wokuhlanganisa we-Benzeneacetonitrile kugxile ekuvikelweni kwemvelo kanye nomnotho we-athomu, ilwela ukunciphisa ukukhishwa kwemfucuza, ukuthuthukisa ukusebenza kahle kokusetshenziswa kwezinsiza, ukufaka isandla ekuthuthukisweni okusimeme kwemboni yamakhemikhali, nokwandisa ukusetshenziswa kwayo. okungenzeka.