i-benzyl 3 6-dihydropyridine-1(2H)-carboxylate (CAS# 66207-23-6)

Isingeniso

I-N-CBZ-1,2,3,6-tetrahydropyridine, eyaziwa nangokuthi i-carbamate-4-hydroxybenzyl ester-1,2,3,6-tetrahydropyridine, iyinhlanganisela yezinto eziphilayo. Okulandelayo yisingeniso sezakhiwo zayo, ukusetshenziswa kwayo, izindlela zokukhiqiza kanye nolwazi lokuphepha:

Ikhwalithi:

- I-N-Cbz-1,2,3,6-tetrahydropyridine iqinile emhlophe.

- Lizinzile ezingeni lokushisa elilingana negumbi kodwa liyabola lapho amazinga okushisa aphezulu.

- Ingancibilika kwezinye izincibilikisi eziphilayo njenge-dimethyl sulfoxide ne-ethanol.

Sebenzisa:

- I-N-Cbz-1,2,3,6-tetrahydropyridine ivame ukusetshenziswa njengeqembu elivikelayo ku-organic synthesis ukuvikela iqembu lama-amino eqenjini le-amine. Ivikela iqembu lama-amino ezimweni ezingathandeki noma amanye ama-reagents ekuphenduleni.

Indlela:

- I-N-Cbz-1,2,3,6-tetrahydropyridine ingalungiswa nge-amination kanye ne-acylation. I-Tetrahydropyridine isabela nge-carbamate ngokusebenzisa ukusabela kwe-aminoation ukukhiqiza i-N-amino-1,2,3,6-tetrahydropyridine. Khona-ke, i-N-amino-1,2,3,6-tetrahydropyridine isabela nge-chloroformate ukwenza i-N-Cbz-1,2,3,6-tetrahydropyridine.

Ulwazi Lokuphepha:

- Kunedatha yobuthi elinganiselwe ye-N-Cbz-1,2,3,6-tetrahydropyridine, kodwa ngokuvamile, ingaba nokucasuka okuthile kanye nobuthi kubantu.

- Gwema ukuthintana ngqo nesikhumba kanye nokuhogela uthuli lwaso ngesikhathi sokusebenzisa.

- Izindlela zokuphepha ezifanele, njengamagilavu ​​nempahla yokuphefumula, kufanele zithathwe ngesikhathi sokuphatha nokugcina.

- Uma usebenzisa futhi ugcina, sicela ulandele imihlahlandlela efanele yokuphatha ngokuphephile kanye nemithethonqubo.