I-BOC-ASP(OBZL)-ONP(CAS# 26048-69-1)
Isingeniso
I-4-Benzyl1-(4-nitrophenyl)(tert-butoxycarbonyl)-L-aspartic acid iyinhlanganisela yezinto eziphilayo. Okulandelayo kuchaza izakhiwo zayo, ukusetshenziswa kwayo, izindlela zokukhiqiza, nolwazi lokuphepha.
Ikhwalithi:
- Ukubukeka: Ngokuvamile amakristalu amhlophe noma i-crystalline powder.
- Ukunyibilika: Kuncibilika kwezinye izincibilikisi eziphilayo njenge-methanol, i-methylene chloride ne-ethanol.
Sebenzisa:
- Ingasetshenziswa njengeqembu elivikela i-amino acid ukuze kuhlanganiswe ukulandelana kwe-peptide.
- I-Boc-L-Aspartic Acid 4-Benzyl 1-(4-Nitrophenyl)Ester ingaphinda isetshenziselwe ukwakha ama-molecule amasha e-bioactive.
Indlela:
Ukulungiswa kwe-4-benzyl1-(4-nitrophenyl)(tert-butoxycarbonyl)-L-aspartic acid ngokuvamile kuhlanganisa izinyathelo ezilandelayo:
I-L-aspartic acid ifakwa esterified nge-Branstri chloride (Boc) ukuze yakhe i-Boc-L-aspartic acid.
I-Boc-L-aspartic acid isabela nge-benzyl alcohol ukukhiqiza i-4-benzyl Boc-L-aspartic acid.
Ngaphansi kwezimo ze-alkaline, i-4-benzyl Boc-L-aspartic acid isabela ngokweqile kwe-4-nitrophenyl iodide ukuze kukhiqizwe i-4-benzyl1-(4-nitrophenyl)Boc-L-aspartic acid.
Umkhiqizo okuhlosiwe, i-4-benzyl1-(4-nitrophenyl)(tert-butoxycarbonyl)-L-aspartic acid, utholwe ngokukhipha ukuvikela i-4-benzyl1-(4-nitrophenyl)(tert-butoxycarbonyl)-L-aspartic acid ngokuyivimba ( ukususa iqembu lokuvikela le-Boc).
Ulwazi Lokuphepha:
- Kunedatha encane yokuphepha yale nhlanganisela, kodwa njengenhlanganisela yezinto eziphilayo, kufanele kuqashelwe ukuze kuvinjelwe ukuhogela, ukuthinta isikhumba, nokungeniswa.
- Izimpahla zokuzivikela ezifanele ezifana namagilavu aselabhorethri, izibuko, namamaski okuzivikela kufanele zigqokwe ngesikhathi sokuphatha.
- Kufanele isetshenziswe endaweni engenawo umoya ukuze kugwenywe ukuvela kothuli.
