I-BOC-D-2-Amino butyric acid (CAS# 45121-22-0)
| I-Hazard Class | I-IRRITANT |
Isingeniso
I-Boc-D-Abu-OH(Boc-D-Abu-OH) iyinhlanganisela yemvelo enezici ezilandelayo:
1. ukubukeka kanye nezakhiwo: isimo somzimba esivamile ikristalu emhlophe noma i-crystalline powder.
2 izakhiwo zamakhemikhali: iwuhlobo lwezinhlanganisela ze-amide, inokuncibilika okuhle, kuzincibilikisi zemvelo (njenge-dimethyl sulfoxide, i-dichloromethane, i-acetone, njll.) ekuncibilikeni okuphezulu.
3. Ukuzinza: kuzinzile ngaphansi kwezimo ezivamile, kodwa ukuthintana nama-oxidants aqinile nezimo zokushisa okuphezulu kufanele kugwenywe.
Izicelo ze-Boc-D-Abu-OH zigxile kakhulu emkhakheni we-organic synthesis, evame ukusetshenziswa kukhemistri yezemithi kanye nocwaningo lwe-biochemistry, izicelo ezithile zifaka:
1. i-peptide synthesis: njengeqembu elivikelayo, ingaba kunqubo ye-peptide synthesis ukuvikela iqembu le-amine, ukulivimbela ekuphenduleni okungaqondile.
2. Ukuhlanganiswa kwezidakamizwa: kungasetshenziswa njengesimaphakathi sokulungiswa kwama-molecule ezidakamizwa ezingase zibe khona kanye nezinhlanganisela zekhandidethi yezidakamizwa.
3. Izifundo zezinto eziphilayo: Okuphuma ku-Boc-D-Abu-OH kungasetshenziswa ukuhlola umsebenzi webhayoloji kanye nezakhiwo ze-pharmacokinetic zezinhlanganisela ezithile.
Indlela yokulungiselela ye-Boc-D-Abu-OH ngokuvamile ifinyelelwa ngezinyathelo ezilandelayo:
1. Sebenzisa ama-reagents afanelekile ukuze uguqule i-methyl propionate ku-dimethyl sulfoxide ibe yi-N-BOC-alanine methyl ester.
2. I-N-BOC-alanine methyl ester iphinde ifakwe emanzini ngaphansi kwezimo ze-alkaline ukuze ikhiqize i-Boc-D-Abu-OH.
mayelana nolwazi lwezokuphepha lwe-Boc-D-Abu-OH, amaphuzu alandelayo kufanele aqashelwe:
1. Uma kubhekwa ukuthi iyikhemikhali, kufanele iphathwe futhi igcinwe ngendlela efanele, igweme ukuthintana nesikhumba namehlo, futhi igweme umlilo.
2. esetshenziswayo kufanele ilandele izinqubo zokuphepha zaselabhorethri.
3. Ukuze kuhlolwe ukuphepha kwamakhemikhali, kufanele kuboniswane namaphepha edatha ephephile afanelekile kanye nezincwadi ukuze kuqinisekiswe ukusetshenziswa okulungile nokuphephile.
