I-Boc-D-aspartic acid 4-benzyl ester (CAS# 51186-58-4)

Isingeniso

I-tert-Butoxycarbonyl-D-aspartic acid 4-benzyl ester (i-Boc-D-aspartic acid 4-benzyl ester) iyinhlanganisela yezinto eziphilayo. Okulandelayo incazelo yezakhiwo, ukusetshenziswa, ukulungiswa kanye nolwazi lokuphepha kwenhlanganisela:

Imvelo:

-Ukubukeka: I-crystalline emhlophe eqinile

-Ifomula ye-molecular: C16H21NO6

Isisindo samangqamuzana: 323.34g/mol

-indawo yokuncibilika: 104-106 ℃

-Ukunyibilika: Kuncibilika kuzincibilikisi ezivamile zemvelo (njenge-ether, i-methanol, i-ethanol)

Sebenzisa:

-tert-Butoxycarbonyl-D-aspartic acid 4-benzyl ester isetshenziswa kakhulu njenge-reagent ocwaningweni lwe-biochemical, esetshenziselwa ukuhlanganiswa noma ukuguqula ezinye izinhlanganisela eziphilayo.

-Ivame ukusetshenziswa ekuhlanganiseni kwe-peptide njengeqembu elivikelayo le-aspartic acid ukuze kuvikelwe iqembu elisebenzayo kuchungechunge lwe-amino acid ohlangothini futhi lenze ukusabela kokuvikela lapho kudingeka.

Indlela Yokulungiselela:

-Ngokujwayelekile, i-Boc-D-aspartic acid 4-benzyl ester ilungiswa ngokusabela kwe-aspartic acid. Okokuqala, i-aspartic acid isabela nge-acetyl chloride (AcCl) ukunikeza i-aspartic acid acetyl ester. I-acetyl evikelwe i-aspartate acetyl ester bese isabela nge-tert-butoxycarbonyl chloride (Boc-Cl) ukuze inikeze i-tert-butoxycarbonyl-D-aspartate 4-acetyl ester. Ekugcineni, i-tert-butoxycarbonyl-D-aspartic acid 4-benzyl ester ingatholwa nge-esterification ye-benzyl alcohol kanye nesisekelo.

Ulwazi Lokuphepha:

- I-Boc-D-aspartic acid 4-benzyl ester ngokuvamile inobuthi obuphansi, kusadingeka ukuthi kuthathwe izinyathelo ezifanele zokuvikela ngesikhathi sokusebenza, njengokugqoka amagilavu, izibuko kanye namajazi aselabhorethri.

-Gwema ukuthinta isikhumba kanye nokuhogela uthuli.

-Kugcine endaweni eyomile, epholile, kude nomlilo nama-oxidizing agents.

-Lapho uphatha futhi ulahla, sicela ulandele izinqubo nemithethonqubo yokusebenza yokuphepha efanele.