I-BOC-D-ASP(OBZL)-OH(CAS# 92828-64-3)

Isingeniso

(3R)-4-(benzyloxy)-3-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid (igama elingakhethwanga)((3R)-4-(benzyloxy)-3-[(tert-butoxycarbonyl) amino]-4-oxobutanoic acid) iyinhlanganisela ephilayo enefomula yamangqamuzana engu-C16H21NO6.

I-compound iphuma ku-aspartic acid enezici ezilandelayo:

-Ukubukeka i-white crystalline powder;

-Izinzile ekamelweni lokushisa, kodwa izobola ekushiseni okuphezulu;

-Incibilika kuzincibilikisi ezivamile ezifana ne-methanol, i-ethanol ne-dichloromethane.

(3R)-4-(benzyloxy)-3-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid (igama elingancanyelwayo) inohlu olubanzi lwezinhlelo zokusebenza emkhakheni wezokwelapha:

-Isetshenziswa njengendawo ephakathi yokuhlanganiswa kwe-polypeptides kanye nezinhlanganisela ezinezinsalela ze-aspartic acid kumaprotheni;

-Ingasetshenziswa futhi njenge-synthetic intermediate yezidakamizwa.

Elabhorethri, indlela yokulungiselela (3R) -4-(benzyloxy)-3-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid (igama elingakhethwa) ngokuvamile iwukusabela kweqembu le-carboxyl le-aspartic acid ne i-tert-butoxycarbonyl isocyanate, futhi yethula amaqembu e-benzyl ester ngokusabela okufanele kokusebenza.

Mayelana nolwazi lokuphepha,(3R)-4-(benzyloxy)-3-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid (igama elingakhethwa) inobuthi obulinganiselwe kanye nedatha yezingozi, ngakho ukusebenza kwayo ngokuphephile kufanele kulandele ilabhorethri evamile. imihlahlandlela yokuphepha. Gqoka izinto zokuzivikela ezifanele njengezingilazi, amagilavu ​​namajazi aselabhorethri ngesikhathi sokusebenzisa noma ukuphatha. Ngesikhathi esifanayo, ukugwema ukuthintana kwayo nama-oxidants aqinile kanye nezinto ezivuthayo.