I-BOC-D-Tyrosine methyl ester (CAS# 76757-90-9)

Isingeniso

I-boc-D-tyrosine methyl ester iyinhlanganisela ephilayo enefomula yamakhemikhali C17H23NO5. Kuyinhlanganisela ye-N-protecting methyl ester ye-D-tyrosine, lapho i-Boc imele i-N-tert-butoxycarbonyl (tert-butoxycarbonyl). I-boc-D-tyrosine ester iyiqembu elivamile elivikela i-amino acid, elingavikela i-nucleophile ekuphenduleni nge-D-tyrosine ekuhlanganiseni.

Ukusetshenziswa okuyinhloko kwe-boc-D-tyrosine methyl ester kunjengento yokuqala noma emaphakathi ku-polypeptide synthesis, futhi isetshenziselwa ukuhlanganisa ama-polypeptides aqukethe i-D-tyrosine. Lokhu kungafezwa ngokungeza iqembu le-N-tert-butoxycarbonyl methyl ku-D-tyrosine.

Indlela yokulungiselela i-boc-D-tyrosine methyl ester ingasebenzisa izimo ezihlukahlukene zokusabela ezihlukene. Indlela yokwenziwa evamile iwukusabela i-D-tyrosine nge-methanol ne-sulfuric acid ukuze kukhiqizwe i-D-tyrosine methyl ester, ephinde iphendule nge-N-tert-butoxycarbonyl isocyanate ukukhiqiza i-boc-D-tyrosine ester.

Mayelana nolwazi lokuphepha, i-boc-D-tyrosine methyl ester ngokuvamile iphephe kakhulu ngaphansi kwezimo zokusebenza ezifanele. Kodwa-ke, iyinhlanganisela yezinto eziphilayo ezingase zicasule futhi zibe nobuthi. Ukusetshenziswa kufanele kulandele izinqubo zokuphepha ezifanele zaselabhorethri, njengokugqoka amagilavu ​​okuzivikela, izibuko, namajazi aselabhorethri, futhi kusebenze endaweni enomoya omuhle. Sebenzisa okokuvikela kwamakhemikhali kanye nezilawuli zobunjiniyela njengoba kudingeka ukuze uvikele ukuphepha komuntu siqu.