I-Boc-L-aspartic acid 1-benzyl ester (CAS# 30925-18-9)
| Incazelo Yokuphepha | 24/25 - Gwema ukuthintana nesikhumba namehlo. |
| I-WGK Germany | 3 |
| Ikhodi ye-HS | 29242990 |
Isingeniso
I-Boc-Asp-OBzl(Boc-Asp-OBzl) iyinhlanganisela enezakhiwo ezilandelayo:
1. Ukubukeka: Okuqinile kwekristalu emhlophe.
2. Ifomula yemolekyuli: C24H27N3O7.
3. Isisindo sengqamuzana: 469.49g/mol.
4. Iphuzu elincibilikayo: cishe ku-130-134 ° C.
I-Boc-Asp-OBzl isetshenziswa kabanzi ku-biochemistry kanye ne-synthetic organic chemistry, evame ukusetshenziswa ekuhlanganiseni ama-peptide, amaprotheni nezidakamizwa, ngokusetshenziswa okulandelayo:
1. I-Peptide synthesis: Njengengxenye yeqembu elivikelayo (iqembu le-Boc elivikelayo), iqembu lama-amino ku-aspartic acid amino acid lingavikelwa.
2. Ucwaningo lwezidakamizwa: ukuhlanganiswa kwezidakamizwa ze-peptide ezine-anti-inflammatory, anti-tumor kanye nomsebenzi wokulawula amasosha omzimba.
3. Ukusabela kwe-Enzyme: I-Boc-Asp-OBzl ingasetshenziselwa i-enzyme catalyzed reaction substrate.
Indlela yokulungiselela i-Boc-Asp-OBzl imi kanje:
I-aspartic acid ne-benzoyl chloride zifakwa esterified ukwenza i-tert-butoxycarbonyl-aspartic acid benzyl ester (Boc-Asp-OMe), esabela kamuva nge-sodium hexoxide ukuze kutholwe okumaphakathi ngendlela ye-N-hexanoate. Ekugcineni, ithola ukusabela kwe-benzoylation ukukhiqiza i-Boc-Asp-OBzl.
Naka ulwazi olulandelayo lokuphepha lapho usebenzisa i-Boc-Asp-OBzl:
1. I-compound ingase ibangele ukucasuka nokungezwani komzimba womuntu, futhi ukuthintana ngqo nesikhumba namehlo kufanele kugwenywe.
2. Izinyathelo ezifanele zokuzivikela kufanele zithathwe ngesikhathi sokusebenza, njengokugqoka amagilavu nezibuko.
3. Gcina womile futhi uvalwe ngesikhathi sokugcina, futhi ugweme umlilo kanye ne-oxidant.
4. Uma usebenzisa futhi uphatha i-Boc-Asp-OBzl, sicela ulandele izinqubo ezifanele zokusebenza zelabhorethri nokusebenza okuphephile.
Sicela uqaphele ukuthi lapho usebenzisa i-Boc-Asp-OBzl nanoma imaphi amakhemikhali, kufanele ulandele ngokuqinile imihlahlandlela yokusebenza kwezokuphepha ehambisanayo, futhi wenze ukuvikela komuntu siqu kanye nokuhlola ubungozi ngokuya ngesimo sangempela.
