I-Boc-L-Glutamic acid (CAS# 2419-94-5)
| Izimpawu Eziyingozi | I-Xn - Iyingozi |
| Amakhodi Engozi | R20/21/22 – Kuyingozi ngokuhogela umoya, ukuthintana nesikhumba futhi uma ukugwinyile. R36/37/38 – Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. |
| Incazelo Yokuphepha | S22 - Ungaphefumuli uthuli. I-S24/25 - Gwema ukuthintana nesikhumba namehlo. S36 – Gqoka izingubo ezifanele zokuzivikela. S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. S4/25 - |
| I-WGK Germany | 3 |
| Ikhodi ye-HS | 29241990 |
Isingeniso
I-Boc-L-glutamic acid iyinhlanganisela yemvelo enegama lamakhemikhali elithi tert-butoxycarbonyl-L-glutamic acid. Okulandelayo yisingeniso sezakhiwo, ukusetshenziswa, izindlela zokulungiselela kanye nolwazi lokuphepha lwe-Boc-L-glutamic acid:
Ikhwalithi:
I-Boc-L-glutamic acid iyikristale emhlophe eqinile encibilika kwezinye izincibilikisi eziphilayo njenge-methanol, i-ethanol, ne-dimethyl sulfoxide. Iyazinza uma kuqhathaniswa nezinga lokushisa elilingana negumbi, kodwa ingase ibole emazingeni okushisa aphezulu.
Sebenzisa:
I-Boc-L-glutamic acid iyinhlanganisela evikelayo evame ukusetshenziswa ekuphenduleni kwe-peptide synthesis ku-organic synthesis. Ivikela iqembu le-carboxyl le-glutamic acid, ngaleyo ndlela ilivimbele ekuphenduleni okuseceleni ekuphenduleni. Uma ukusabela sekuqediwe, iqembu elivikelayo le-Boc lingasuswa ngokusabela kwe-asidi noma kwe-hydrogenation, okuholela ekwakhekeni kwe-peptide yentshisekelo.
Indlela:
I-Boc-L-glutamic acid ingatholwa ngokusabela i-L-glutamic acid nge-tert-butylhydroxycarbamoyl (BOC-ON). Ukusabela kwenzeka ku-solvent ye-organic, ngokuvamile emazingeni okushisa aphansi, futhi i-catalyzed by base.
Ulwazi Lokuphepha:
Ukusetshenziswa kwe-Boc-L-glutamate kufanele kulandele izinqubo zokuphepha zaselabhorethri. Uthuli lwayo lungase lucasule isimiso sokuphefumula, amehlo nesikhumba, nezinto zokuzivikela ezinjengama-respirators, izibuko zokuzivikela namagilavu kufanele kugqokwe lapho uphathwa. Kufanele igcinwe endaweni eyomile, epholile ukugwema ukuthintana nama-oxidants nama-acids aqinile nezisekelo. Uma ungenwa ngephutha noma uthintane nesikhumba, funa usizo lwezempilo noma uthintane nochwepheshe ngokushesha.
