CBZ-D-ALLO-ILE-OH(CAS# 55723-45-0)
Isingeniso
ZD-allo-Ile-OH . I-DCHA (ZD-allo-Ile-OH · DCHA) iyinhlanganisela yezinto eziphilayo kanye ne-reagent yokuvikela ama-amino acid. Okulandelayo yincazelo yemvelo yayo, ukusetshenziswa, ukwakhiwa kanye nolwazi lokuphepha:
Imvelo:
-Ifomula yamakhemikhali: C23H31NO5
Isisindo samangqamuzana: 405.50g/mol
-Ukubukeka: I-crystalline emhlophe eqinile
-Indawo yokuncibilika: 105-108°C
-I-Solubility: I-Soluble ku-organic solvents njenge-acetone, i-ether, i-dichloromethane, engancibiliki emanzini.
Sebenzisa:
- ZD-allo-Ile-OH . I-DCHA iyi-reagent esetshenziselwa ukuvikela ama-amino acid. Ngokwethula iqembu le-Cbz eqenjini le-amino le-amino acid, ukuguqulwa ngephutha kweqembu lama-amino ekuphenduleni kwamakhemikhali kungavinjelwa.
-Ivame ukusetshenziswa ekuhlanganiseni kwe-peptide, ikakhulukazi ukuhlanganiswa kokulandelana kwe-peptide ngezakhiwo ezikhethekile noma imisebenzi.
Indlela Yokulungiselela:
- ZD-allo-Ile-OH. Ukulungiswa kwe-DCHA kuvame ukuqala ku-D-isoleucine, bese isabela nge-Cbz anhydride ukuze i-esterification yethule iqembu lokuvikela le-Cbz. Ekugcineni, i-DCHA (i-dichloroformic acid) isabela nge-amino acid ukuze yakhe usawoti ohambisanayo.
Ulwazi Lokuphepha:
- ZD-allo-Ile-OH . I-DCHA ayinabo ubuthi obuncane, kodwa kufanele iphathwe ngokuqapha. Gwema ukuthinta isikhumba namehlo, gqoka amagilavu okuzivikela kanye nezibuko uma kunesidingo.
-Ngesikhathi sokusetshenziswa, izinqubo ezijwayelekile zokusebenza zaselabhorethri kufanele zilandelwe futhi kusetshenziswe imishini efanele yokukhipha umoya.
-Lapho ugcina, gcina inkomishi endaweni eyomile, epholile kude nemithombo yomlilo namalangabi avulekile.
