I-D-1-N-Boc-prolinamide (CAS# 35150-07-3)

Isingeniso

I-D-1-N-Boc-prolinamide(D-1-N-Boc-prolinamide) iyinhlanganisela yemvelo enezici ezilandelayo:

1. Ukubukeka: Okuqinile kwekristalu emhlophe.

2. ifomula yamangqamuzana: C14H24N2O3.

3. Isisindo sengqamuzana: 268.35g/mol.

4. indawo encibilikayo: cishe ama-75-77 degrees Celsius.

5. Ukunyibilika: Kuncibilika emanzini nakwezinye izincibilikisi eziphilayo, njenge-chloroform, i-ethanol ne-dimethyl sulfoxide.

Okunye ukusetshenziswa okuyinhloko kwe-D-1-N-Boc-prolinamide kufana ne-chiral reagent ye-asymmetric synthesis ku-organic chemical synthesis. Ingasetshenziswa njengesakhiwo se-chiral skeleton ukwethula ulwazi lwe-chiral ngokusebenzisa isikhungo sayo se-chiral, ngaleyo ndlela ithole ama-chiral compounds. Ngaphezu kwalokho, ingasetshenziswa futhi njengendawo ephakathi yokuhlanganiswa kwezidakamizwa, izibulala-zinambuzane nama-molecule e-bioactive.

Indlela yokulungisa i-D-1-N-Boc-prolinamide imvamisa ukusabela i-N-Boc-L-proline ne-tert-butyl chloroformate ngaphansi kwezimo ze-alkaline ukukhiqiza i-N-Boc-L-proline methyl ester emaphakathi, bese ukwelashwa ukushisa khiqiza umkhiqizo ohlosiwe.

Mayelana nolwazi lokuphepha, ucwaningo oluningiliziwe lwe-toxicological lushoda nge-D-1-N-Boc-prolinamide. Kodwa-ke, ngokuvamile, imisebenzi yokuphepha yaselabhorethri kufanele ilandelwe, futhi izinyathelo zokuzivikela ezifana namagilavu, izibuko nezingubo zokuzivikela kufanele zinakwe lapho kusetshenziswa. Ngaphezu kwalokho, kufanele igcinwe esitsheni esivaliwe ukugwema ukuthintana ne-oxygen nomswakama. Uma uhogelwe ngephutha noma uthintane nesikhumba namehlo, geza ngokushesha ngamanzi amaningi futhi ufune usizo lwezokwelapha. Uma kuzolahlwa imfucuza, kufanele kulandelwe imithetho yendawo. Kungcono ukusebenzisa futhi uphathe i-compound ngaphansi kokuqondisa komuntu onesizinda sobuchwepheshe kukhemistri.