D-2-Amino-3-phenylpropionic acid (CAS# 673-06-3)
| Amakhodi Engozi | 34 - Ibangela ukusha |
| Incazelo Yokuphepha | I-S24/25 - Gwema ukuthintana nesikhumba namehlo. S45 – Uma kwenzeka ingozi noma uzizwa ungaphilile, funa iseluleko sezokwelapha ngokushesha (bonisa ilebula noma nini lapho kunokwenzeka.) S36/37/39 – Gqoka izingubo zokuzivikela ezifanele, amagilavu kanye nokuvikela iso/ubuso. S27 – Khumula ngokushesha zonke izingubo ezingcolile. S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. |
| I-WGK Germany | 3 |
| I-RTECS | AY7533000 |
| I-TSCA | Yebo |
| Ikhodi ye-HS | 29224995 |
| Inothi Lengozi | Iyacasula |
| Ubuthi | I-TDLo orl-hmn: 500 mg/kg/5W-I:GIT JACTDZ 1(3),124,82 |
Isingeniso
I-D-phenylalanine iyiprotheyini eluhlaza enegama lekhemikhali elithi D-phenylalanine. Yakheka ku-D-configuration ye-phenylalanine, i-amino acid yemvelo. I-D-phenylalanine iyafana ngokwemvelo ne-phenylalanine, kodwa inemisebenzi ehlukene yebhayoloji.
Ingasetshenziswa njengempahla eluhlaza emithini, emikhiqizweni yezempilo kanye nezithako zokudla okunomsoco ukuze kuthuthukiswe umsebenzi wesimiso sezinzwa esimaphakathi nokulawula ibhalansi yamakhemikhali emzimbeni. Ibuye isetshenziswe ekuhlanganiseni kwezinhlanganisela ezine-antitumor kanye nemisebenzi ye-antimicrobial.
Ukulungiswa kwe-D-phenylalanine kungenziwa nge-chemical synthesis noma i-biotransformation. Izindlela zokuhlanganisa amakhemikhali ngokuvamile zisebenzisa ukusabela kwe-enantioselective ukuze kutholwe imikhiqizo enokulungiselelwa kwe-D. Indlela ye-biotransformation isebenzisa isenzo se-catalytic sama-microorganisms noma ama-enzyme ukuguqula i-phenylalanine yemvelo ibe yi-D-phenylalanine.
Kuyinhlanganisela engazinzile esengozini yokucekelwa phansi ukushisa nokukhanya. Ukudla ngokweqile kungase kubangele ukuphazamiseka kwamathumbu. Enqubweni yokusebenzisa i-D-phenylalanine, umthamo kufanele ulawulwe ngokuqinile, futhi kulandelwe izinqubo ezifanele zokusebenza zokuphepha. Kubantu ngabanye abangezwani ne-D-phenylalanine noma abane-phenylalanine metabolism engavamile, kufanele kugwenywe noma kusetshenziswe ngaphansi kokuqondisa kukadokotela.
