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I-D(-)-Glutamic acid (CAS# 6893-26-1) Isithombe Esifakiwe
  • I-D(-)-Glutamic acid (CAS# 6893-26-1) 1

I-D(-)-Glutamic acid (CAS# 6893-26-1)

Isakhiwo Samakhemikhali:

I-Molecular Formula I-C5H9NO4
I-Molar Mass 147.13
Ukuminyana 1.5380
I-Melting Point 200-202°C (subl.)(lit.)
I-Boling Point 267.21°C (isilinganiso esinzima)
Ukuzungezisa Okuthile(α) -31.3 º (c=10, 2 N HCl)
I-Flash Point 155.7°C
Ukuncibilika kwamanzi 7 g/L (20 ºC)
Ukuncibilika Amanzi (Kancane)
I-Vapor Presure 2.55E-05mmHg ku-25°C
Ukubukeka Ikristalu elimhlophe
Umbala Okumhlophe kuya kokumhlophe
I-Merck 14,4469
I-BRN 1723800
pKa pK1:2.162(＋1);pK2:4.272(0);pK3:9.358(－1) (25°C)
Isimo Sesitoreji Gcina endaweni emnyama, evalwe endaweni eyomile, Emazingeni Okushisa Egumbi
I-Refractive Index 1.4210 (isilinganiso)
I-MDL I-MFCD00063112
Izakhiwo Zomzimba Nezamakhemikhali I-crystal emhlophe noma i-crystalline powder; Incibilika emanzini, inyibilika kancane ku-ethanol, ayincibiliki ku-ether; Ukujikeleza okuqondile kokubona [α]20D-30.5 °(0.5-2 mg/mL, 6mol/L HCl), LD50 (omuntu, emthanjeni) 117 mg/kg.
Sebenzisa Izidakamizwa ze-amino acid.
Isifundo se-in vitro Ama-d-amino acid ahlukahlukene, afana ne-D-serine, i-D-aspartic acid (D-Asp), ne-D-glutamic acid (D-Glu) atholakala kakhulu ezilwaneni ezincelisayo okuhlanganisa nabantu futhi manje sekucatshangwa ukuthi yizo. inoveli yezinto eziphilayo ezisebenzayo kanye/noma ama-biomarker. I-D-[Asp/Glu] (4 mg/mL) ivimbela ukubophezela kwe-IgE (75%) kumakinati kuyilapho i-D-Glu, i-D-Asp ingenawo umthelela ovimbelayo. I-IgE icaciselwe i-D-[Asp/Glu] futhi ingase ibe namandla okukhipha i-IgE noma yehlise ukubophezela kwe-IgE ezintweni ezingezwani nephenathi.
Isifundo se-vivo I-D-glutamic acid njengamanje inakwa njengemoduli yokudluliswa kwe-neuronal kanye nokukhiqizwa kwamahomoni. I-metabolized kuphela yi-D-aspartate oxidase ezilwaneni ezincelisayo. Ngemuva komjovo we-intraperitoneal, i-L-glutamate yenziwa i-a-ketoglutarate, kuyilapho i-D-glutamate iguqulwa ibe yi-n-pyrrolidone carboxylic acid. I-Carbon 2 yakho kokubili i-D- ne-L-glutamate iguqulwa ku-cecum ibe yi-methyl carbon ye-acetate. Kokubili isibindi segundane nezinso zenza ukuguqulwa kwe-D-glutamic acid ibe yi-n-pyrrolidone carboxylic acid.

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Izimpawu Eziyingozi Xi - Irritant
Amakhodi Engozi 36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
Incazelo Yokuphepha I-S24/25 - Gwema ukuthintana nesikhumba namehlo.
S36 – Gqoka izingubo ezifanele zokuzivikela.
S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
I-WGK Germany 3
AMAKHODI E-FLUKA BRAND F 10
I-TSCA Yebo
Ikhodi ye-HS 29224200

 

Isingeniso

I-D-glutenate, eyaziwa nangokuthi i-D-glutamic acid noma i-sodium D-glutamate, iyi-amino acid eyenzeka ngokwemvelo enezakhiwo ezihlukahlukene ezibalulekile nokusetshenziswa.

 

Izici eziyinhloko ze-D-gluten zimi kanje:

Ukunambitheka okumaphakathi: I-D-gluten iyisithuthukisi se-umami esithuthukisa ukunambitheka kwe-umami kokudla futhi sithuthukise ukunambitheka kokudla.

Isengezo Somsoco: I-D-gluten ingenye yama-amino acid abalulekile emzimbeni womuntu futhi idlala indima ebalulekile ekugcineni impilo yomuntu.

Izinzile ngokwekhemikhali: I-D-glunine izinzile uma kuqhathaniswa ngaphansi kwezimo ezine-asidi futhi ingagcina ukuqina okuhlobene ngaphansi kwezimo zokushisa eziphezulu.

 

Ukusetshenziswa kwe-D-Gluten Acid:

Ucwaningo lwe-Biochemical: I-D-glutamic acid isetshenziswa kabanzi ocwaningweni lwe-biochemical kanye nokuhlolwa ukuze kufundwe ukusabela kwayo kwamakhemikhali ezinto eziphilayo kanye nezindlela ze-metabolic ezintweni eziphilayo.

 

Indlela yokulungiselela i-D-gluten itholakala ikakhulukazi ngokuvutshelwa kwe-microbial noma ukuhlanganiswa kwamakhemikhali. Ukukhiqizwa kwe-Microbial fermentation okwamanje kuyindlela eyinhloko yokulungiselela, kusetshenziswa izinhlobo ezithile ukukhiqiza inani elikhulu le-D-glutamic acid ngokuvutshelwa. Ukuhlanganiswa kwamakhemikhali ngokuvamile kusebenzisa izinto zokwenziwa zokwenziwa kanye nezimo ezithile zokusabela ukuze kuhlanganiswe i-D-gluten acid.

 

Ulwazi Lokuphepha lwe-D-Gluten: Ngokuvamile, i-D-Gluten iphephile ngaphansi kwezimo zokusetshenziswa nokugcinwa okufanele. Ukwengeza, kubantu abathile, njengezinsana nabesifazane abakhulelwe, noma labo abanokuzwela kwe-glutamate, kungase kufaneleke kakhulu ukusebenzisa noma ukugwema i-D-glutamate ngokulinganisela.

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