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I-D-Glutamine (CAS# 5959-95-5) Isithombe Esifakiwe
  • I-D-Glutamine (CAS# 5959-95-5) 1

I-D-Glutamine (CAS# 5959-95-5)

Isakhiwo Samakhemikhali:

I-Molecular Formula C5 H10 N2 O3
I-Molar Mass 146.14
Ukuminyana 1.3394 (isilinganiso esinzima)
I-Melting Point 184-185 °C
I-Boling Point 265.74°C (isilinganiso esinzima)
Ukuzungezisa Okuthile(α) -32 º (589nm, c=10, N HCl)
Ukuncibilika kwamanzi 42.53g/L(izinga lokushisa alishiwongo)
Ukuncibilika Incibilika emanzini (9 mg/ml ku-25 °C), i-DMSO (<1 mg/ml ku-25 °C), ne-ethanol (<1 mg/m
Ukubukeka I-crystalline powder emhlophe
Umbala Emhlophe
I-BRN 1723796
pKa 2.27±0.10(Okubikezelwe)
Isimo Sesitoreji Gcina endaweni emnyama, emkhathini ongangeni, izinga lokushisa legumbi
I-Refractive Index -33 ° (C=5, 5mol/LH
I-MDL I-MFCD00065607
Izakhiwo Zomzimba Nezamakhemikhali Indawo encibilikayo: 185
Isifundo se-in vitro I-Glutamine iyi-amino acid eyinhloko ohlelweni lwezinzwa oluphakathi (CNS), edlala indima ebalulekile kumjikelezo we-glutamate/GABA-Glutamine (GGC). Ku-GGC, i-Glutamine idluliswa isuka kuma-astrocyte iye kuma-neurons, lapho izogcwalisa khona amachibi e-neurotransmitter avimbelayo najabulisayo. I-D-Glutamine isetshenziselwe ukutadisha indima yayo ekunikezeni isivikelo ekuphazamisekeni okubangelwa i-acetaldehyde yokusebenza kwesithiyo ku-Caco-2 cell monolayer. Iqhaza le-L-Glutamine ekuvikelweni kwe-epithelium yamathumbu ekuphazanyisweni okudalwe yi-acetaldehyde yomsebenzi wokuvimba ihlolwa ku-Caco-2 cell monolayer. I-L-Glutamine inciphise ukwehla okubangelwa i-acetaldehyde ekuphikisweni kukagesi we-transepithelilal kanye nokwanda kokungena ku-inulin ne-lipopolysaccharide ngendlela encike esikhathini kanye nomthamo; I-D-Glutamine, i-L-aspargine, i-L-arginine, i-L-lysine, noma i-L-alanine ayikhiqizanga ukuvikeleka okubalulekile. I-D-Glutamine iphinde yehluleke ukuba nomthelela ekwehleni okubangelwa i-acetaldehyde ku-TER kanye nokwanda kwe-inulin flux. I-D-Glutamine noma i-glutaminase inhibitor ngokwayo ayizange ibe nomthelela ku-TER noma i-inulin flux ekulawuleni noma ama-cell monolayers aphethwe i-acetaldehyde. Ukuntuleka komphumela we-D-Glutamine ekuvikelweni kwe-acetaldehyde kubonisa ukuthi ukuvikelwa kwe-L-Glutamine-mediated ku-stereospecific.

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Izimpawu Eziyingozi Xi - Irritant
Amakhodi Engozi 36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
Incazelo Yokuphepha S36/37/39 – Gqoka izingubo zokuzivikela ezifanele, amagilavu ​​kanye nokuvikela iso/ubuso.
S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
S27 – Khumula ngokushesha zonke izingubo ezingcolile.
I-S24/25 - Gwema ukuthintana nesikhumba namehlo.
I-WGK Germany 3
Ikhodi ye-HS 29241900

 

Isingeniso

I-isomer engeyona eyemvelo ye-glutamine empeleni ayincibiliki ku-methanol, i-ethanol, i-ether ne-benzene.

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