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I-Ethyl 3-(2-((4-cyanophenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate（CAS# 211915-84-3 ) Isithombe Esifakiwe
  • I-Ethyl 3-(2-((4-cyanophenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate（CAS# 211915-84-3 ) 1

I-Ethyl 3-(2-((4-cyanophenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate（CAS# 211915-84-3 )

Isakhiwo Samakhemikhali:

I-Molecular Formula I-C27H26N6O3
I-Molar Mass 482.53
Ukuminyana 1.25±0.1 g/cm3(Kubikezelwe)
I-Melting Point 149-151°C
I-Boling Point 756.4±60.0 °C(Kubikezelwe)
I-Flash Point 411.245°C
Ukuncibilika I-DMSO (Kancane, I-Sonicated), i-Methanol (Kancane Kancane, I-Sonicated)
I-Vapor Presure 0mmHg ku-25°C
Ukubukeka Okuqinile
Umbala Okumhlophe kuya ku-Pale Beige
pKa 4.21±0.10(Okubikezelwe)
Isimo Sesitoreji Gcina endaweni emnyama, emkhathini ongangeni, izinga lokushisa legumbi
I-Refractive Index 1.64

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

 

Isingeniso

N-[[2-[[(4-cyanobenzenyl)amine]methyl]-1methyl-1H-5-benzimidazole]carbonyl]3-aminobenzoyl]N-2-pyridyl-b-alanine ethyl ester, esifushanisiwe njengokuthi N-PCBMITPAAE. Okulandelayo yisingeniso semvelo yayo, ukusetshenziswa, ukulungiswa kanye nolwazi lokuphepha:

 

Ikhwalithi:

Ukubukeka: Ikristalu eliqinile elingenambala noma eliphuzi elikhanyayo.

Ukunyibilika: I-N-PCBMITPAAE iyancibilika kwezinye izinyibilikisi zemvelo, njenge-dimethyl sulfoxide ne-dichloromethane. Cishe ayincibiliki emanzini.

 

Sebenzisa:

I-N-PCBMITPAAE ivame ukusetshenziswa ocwaningweni lokwenziwa emkhakheni wamakhemikhali. Inesakhiwo samangqamuzana esiyinkimbinkimbi namaqembu asebenzayo, futhi ingasetshenziswa njenge-reagent, i-catalyst noma i-ejenti yokwengeza ku-organic synthesis.

 

Indlela:

Indlela yokulungiselela ye-N-PCBMITPAAE iyinkimbinkimbi futhi ngokuvamile idinga ukusabela kwezinyathelo eziningi. Indlela evamile yokulungiselela ihlanganisa lezi zinyathelo ezilandelayo: ukuhlanganiswa kwe-4-cyanoaniline ne-1-methyl-1H-5-benzimidazole, bese isabela nge-carboatelic acid ukwenza i-N--[(4-cyanobenzene)methyl]-1-methyl-1H- 5-benzimidazole-2-carboxylate. Okulandelayo, isabela nge-3-aminobenzoyl chloride yakhe i-N- [(4-cyanobenzene)methyl]-1-methyl-1H-5-benzimidazole-2-carboxylic acid 3-aminobenzoyl ester. Umkhiqizo wokugcina, i-N-PCBMITPAAE, ukhiqizwa ukusabela nge-2-pyridyl-β-alanine ethyl ester.

 

Ulwazi Lokuphepha:

Isakhiwo se-N-PCBMITPAAE siyinkimbinkimbi kakhulu, futhi ukuqapha kuyadingeka ngesikhathi sokusetshenziswa nokusebenza. Izinqubo ezifanele zaselabhorethri kufanele zilandelwe futhi kufanele kuthathwe izinyathelo ezifanele, njengokugqoka amagilavu ​​okuzivikela, izihlangu zobuso, nezingubo zamehlo ezivikelayo. Kufanele igcinwe kude nemithombo yokuthungela kanye nama-oxidizing aqinile, futhi izimo zokungena komoya ezinhle kufanele zigcinwe. Lapho ugcina futhi uphatha ikhemikhali, sicela uyiphathe ngendlela efanele ukuze uvimbele izingozi.

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