ethyl 3-(4-(methylamino)-3-nitro-N-(pyridin-2-yl)benzamido)propanoate(CAS# 429659-01-8)

Isingeniso

I-Ethyl 3-(4-(methylamino)-3-nitro-N-(pyridin-2-yl)benzoylamido)propionate, eyaziwa nangokuthi i-MTT (Meta-Toluidine ortho-Toluenesulphonic acid triazine ester), iyikhemikhali. Inezici ezilandelayo:

Ukubukeka: Okuqinile okumhlophe

I-Solubility: Incibilika kuma-alcohols, ama-ketones kanye ne-chloroform

Ukusetshenziswa okuyinhloko kwe-MTT kungokulandelayo:

Ucwaningo lwebhayoloji: I-MTT isetshenziswa kakhulu ukunquma ukwanda kwamaseli kanye nokusebenza kwamaseli. Iguqula i-MTT ibe umkhiqizo oluhlaza okwesibhakabhaka oncibilika kumaseli ngokuwehlisa, ongasetshenziswa ukunquma ukusebenza kweseli.

Ngokuvamile, indlela yokulungiselela i-MTT ingenziwa ngezinyathelo ezilandelayo:

I-Methylaniline isabela nge-2-nitrobenzoyl chloride ukuze ithole i-3-(4-methylaminobenzoyl) benzoyl chloride.

Umkhiqizo otholwe esinyathelweni soku-1 usabela nge-2-pyridone ukukhiqiza i-3-(4-methylaminobenzoylamido) benzoyl chloride.

Umkhiqizo otholwe esinyathelweni sesi-2 uphendulwa nge-ethyl 3-aminopropionate ukuze ukhiqize i-ethyl 3-(4-methylaminobenzoylamido)propionate.

Umkhiqizo wokugcina, i-MTT, uhlanzwa nge-crystallization noma ezinye izindlela.

Ulwazi Lokuphepha: I-MTT iwubuthi, futhi kufanele kuqashelwe ukuze uyisebenzise futhi uyilahle ngendlela efanele. Izimpahla zokuzivikela ezifanele njengamagilavu, izibuko, nezingubo zaselabhorethri zidinga ukugqokwa ngesikhathi sokusebenza. Gwema ukuhogela, ukuthinta isikhumba, nokudla. Lapho usebenzisa noma ulahla imfucuza, landela izinqubo ezifanele zokusebenza zokuphepha, futhi ulahle ngokushesha futhi uhlanze noma yikuphi ukuchayeka ungahlosile. Uma kwenzeka uhogela umoya noma ukuthinta isikhumba, funa usizo lwezempilo ngokushesha.