I-Ethyl cyanoacetate(CAS#105-56-6)
| Izimpawu Eziyingozi | Xi - Irritant |
| Amakhodi Engozi | R36/38 – Ukucasuka emehlweni nasesikhunjeni. |
| Incazelo Yokuphepha | S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. I-S37/39 – Gqoka amagilavu afanelekile kanye nokuvikela iso/ubuso |
| Ama-ID e-UN | I-UN 2666 |
I-Ethyl cyanoacetate(CAS#105-56-6) Isingeniso
I-Ethyl cyanoacetate, inombolo ye-CAS 105-56-6, iyimpahla ebalulekile yamakhemikhali ephilayo.
Ngokwesakhiwo, iqukethe iqembu le-cyano (-CN) kanye neqembu le-ethyl ester (-COOCH₂CH₃) ku-molecule yayo, futhi le nhlanganisela yezakhiwo iyenza ihluke ngamakhemikhali. Ngokuphathelene nezakhiwo ezibonakalayo, ngokuvamile iwuketshezi oluphuzi olungenambala olukhanyayo olunephunga elikhethekile, indawo yokuncibilika engaba ngu-22.5 °C, indawo yokubilisa ebangeni lika-206 – 208 °C, elincibilika kuzincibilikisi zemvelo ezifana notshwala. nama-ether, kanye nokuncibilika okuthile emanzini kodwa kuncane uma kuqhathaniswa.
Ngokuphathelene nezakhiwo zamakhemikhali, i-polarity eqinile yeqembu le-cyano kanye nezici ze-esterification zeqembu le-ethyl ester inquma ukuthi lingakwazi ukusabela okuningi. Isibonelo, iyi-nucleophile yakudala, futhi iqembu le-cyano lingabamba iqhaza ekuphenduleni kokungeza kukaMichael, futhi ukuhlanganisa okuhlanganisayo nge-α,β-unsaturated carbonyl compounds kungasetshenziswa ukwakha izibopho ze-carbon-carbon entsha, ezihlinzeka ngendlela ephumelelayo ukuhlanganiswa kwama-molecule ezinto eziphilayo eziyinkimbinkimbi. Amaqembu e-ethyl ester angenziwa nge-hydrolyzed ngaphansi kwezimo ezine-acidic noma ze-alkaline ukuze akhe ama-carboxylic acid ahambisanayo, abalulekile ekuguqulweni kwamaqembu asebenzayo ku-organic synthesis.
Mayelana nendlela yokulungiselela, i-ethyl chloroacetate ne-sodium cyanide zivame ukusetshenziswa njengezinto zokusetshenziswa ukuze zilungiswe ngokuphendula kwe-nucleophilic substitution, kodwa le nqubo idinga ukulawula ngokuqinile umthamo kanye nezimo zokusabela ze-sodium cyanide, ngenxa yobuthi bayo obuphezulu nokusebenza okungalungile. kulula ukubangela izingozi zokuphepha, futhi kuyadingeka futhi ukunaka izinyathelo zokuhlanza ezilandelwayo ukuze uthole imikhiqizo ehlanzekile.
Ezisetshenziswa zezimboni, kuyisihluthulelo esimaphakathi ekuhlanganisweni kwamakhemikhali amahle njengemithi, izibulala-zinambuzane, namakha. Kwezokwelapha, isetshenziselwa ukukhiqiza izidakamizwa ezilalisa-hypnotic ezifana nama-barbiturates; Emkhakheni wezibulala-zinambuzane, hlanganyela ekuhlanganisweni kwezinhlanganisela nemisebenzi yokubulala izinambuzane neyokubulala ukhula; Ekuhlanganiseni kwamakha, ingakha uhlaka lwamathambo ama-flavour akhethekile futhi inikeze izinto zokusetshenziswa eziyingqayizivele zokuxuba ukunambitheka okuhlukahlukene, okudlala indima ebalulekile ekusekeleni imboni yesimanje, ezolimo kanye nezimboni zezimpahla zabathengi.
Kufanele kugcizelelwe ukuthi ngenxa yeqembu le-cyano, i-Ethyl cyanoacetate inobuthi obuthile kanye nomphumela ocasulayo esikhumbeni, amehlo, umgudu wokuphefumula, njll, ngakho-ke kuyadingeka ukugqoka imishini yokuzivikela endaweni enomoya omuhle ngesikhathi sokusebenza, futhi landela ngokuqinile imithetho yokuphepha yamalabhorethri amakhemikhali nokukhiqizwa kwamakhemikhali.
