I-Ethyl L-pyroglutamate (CAS# 7149-65-7)

I-Molecular Formula	I-C7H11NO3
I-Molar Mass	157.17
Ukuminyana	1.2483 (isilinganiso esinzima)
I-Melting Point	54-56°C
I-Boling Point	176°C12mm Hg(lit.)
Ukuzungezisa Okuthile(α)	-3.5 º (c=5, amanzi)
I-Flash Point	>230°F
Ukubukeka	Ukuncibilika Okuphansi Okuqinile
Umbala	Okumhlophe kuya kukhilimu
I-BRN	82621
pKa	14.78±0.40(Okubikezelwe)
Isimo Sesitoreji	Gcina endaweni emnyama, evalwe endaweni eyomile, Emazingeni Okushisa Egumbi
I-Refractive Index	1.4310 (isilinganiso)
I-MDL	I-MFCD00064497

Imininingwane Yomkhiqizo

Izimpawu Eziyingozi	Xi - Irritant
Amakhodi Engozi	36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
Incazelo Yokuphepha	S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. S36 – Gqoka izingubo ezifanele zokuzivikela. I-S37/39 – Gqoka amagilavu afanelekile kanye nokuvikela iso/ubuso
I-WGK Germany	3
AMAKHODI E-FLUKA BRAND F	3-10
Ikhodi ye-HS	29339900

Isingeniso	I-ethyl L-pyroglutamate iwumbala omhlophe kuya kokhilimu, okuqinile okuncibilika okuphansi okuphuma ku-amino acid okungeyona eyemvelo, ama-amino acid angewona awemvelo asetshenziswe kuma-bacterium, imvubelo namaseli ezincelisayo ukuze kuguqulwe amaprotheni, asetshenziswe ocwaningweni oluyisisekelo nasemuthini. ukuthuthukiswa, ubunjiniyela bezinto eziphilayo kanye neminye imikhakha, isetshenziswa kabanzi ukuthola izinguquko zesakhiwo samaprotheni, ukuhlanganisa izidakamizwa, ama-biosensors nokunye.
Sebenzisa	I-ethyl L-pyroglutamate ingasetshenziswa njengamamolekyuli asebenzayo kwezemithi kanye nezimaphakathi ku-organic synthesis, isibonelo, ama-molecule asebenzayo ezinto eziphilayo njenge-HIV integrase inhibitors. Ekuguqulweni kokwenziwa, i-athomu ye-nitrogen eqenjini le-amide ingase ihlanganiswe ne-iodobenzene, futhi i-hydrogen ku-athomu ye-nitrogen ingase iguqulelwe ibe i-athomu ye-chlorine. Ngaphezu kwalokho, iqembu le-ester lingase liguqulwe libe umkhiqizo we-amide ngokusabela kokushintshaniswa kwe-urethane.
indlela yokwenziwa	engeza I-L-pyroglutamic acid (5.00g), i-P-toluenesulfonic acid monohydrate (369 mg, 1.94 mmol) ne-ethanol (100) mL) zanyakaziswa ubusuku bonke ekushiseni kwegumbi, okusele kwachithwa ku-500 EtOAc, isixazululo sanyakaziswa nge-potassium carbonate futhi (ngemuva kokuhlunga), ungqimba lwe-organic lomiswa ngaphezulu. I-MgSO4, futhi isigaba se-organic sasigxilwe ku-vacuo ukunikeza i-ethyl L-pyroglutamate. Umfanekiso we-1 we-ethyl L-pyroglutamate