I-Fmoc-11-Aminoundecanoic acid (CAS# 88574-07-6)
| Izimpawu Eziyingozi | Xi - Irritant |
| Amakhodi Engozi | 36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. |
| Incazelo Yokuphepha | S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. S36 – Gqoka izingubo ezifanele zokuzivikela. |
| I-WGK Germany | 3 |
| I-Hazard Class | I-IRRITANT |
Isingeniso
I-11-(FMOC-amino)undecanoic acid, eyaziwa nangokuthi i-FMOC-11-AMINOUNDECANOIC ACID. Okulandelayo yisingeniso semvelo yayo, ukusetshenziswa, izindlela zokukhiqiza kanye nolwazi lokuphepha:
Ikhwalithi:
- Ukubukeka: 11-(FMOC-amino)i-undecanoic acid iyikristale eqinile emhlophe.
- Ukunyibilika: Kungancibilika kwezinye izinyibilikisi zemvelo njenge-chloroform, i-dimethyl sulfoxide, ne-methylene chloride, kodwa ukuncibilika okuncane emanzini.
Sebenzisa:
- Ucwaningo lwe-Biochemical: 11-(FMOC-amino) i-undecanoic acid ivamise ukusetshenziswa njengesivikelo nesicupha ku-peptide synthesis kanye nocwaningo.
- Ukuhlaziywa kwamakhemikhali: Kungasetshenziswa njengezinga elijwayelekile noma langaphakathi ekuhlaziyeni i-amino acid.
Indlela:
Ukulungiswa kwe-11-(FMOC-amino) undecanoic acid kungenziwa ngezinyathelo ezilandelayo:
- Hlanganisa i-11-aminoundecanoic acid nama-dioxin kanye ne-tetrahydrofuran bese kancane kancane wengeze i-trichlorotrimethylphosphoketone (TMSCl) ngenkathi upholisa futhi uvuselela.
- Bese ufudumeza ingxube ekamelweni lokushisa ngaphambi kokwengeza i-trifluoromethanesulfonic acid (TfOH).
- Isixazululo se-N-(9-fluoroformyl) morphine amide ester sengeziwe, futhi ngemva kokusabela nokuhlanzwa, kwatholakala umkhiqizo omsulwa.
Ulwazi Lokuphepha:
Ulwazi lokuphepha olumayelana ne-11-(FMOC-amino)undecanoic acid okwamanje aluvamile ukubikwa, kodwa izinyathelo zokuphepha zokuphathwa kwaselabhorethri nokusetshenziswa kwamakhemikhali kufanele zilandelwe. Gqoka izinto zokuzivikela ezifanele uma usebenzisa, gwema ukuthinta isikhumba namehlo, futhi uqiniseke ukuthi uyayisebenzisa endaweni enomoya omuhle. Uma kunesidingo, sicela ubheke Ishidi Ledatha Yezokuphepha (SDS) ukuze uthole ulwazi oluningiliziwe lokuphepha.
