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umkhiqizo

I-Fmoc-D-Cyclohexyl glycine (CAS# 198543-96-3)

Isakhiwo Samakhemikhali:

I-Molecular Formula I-C23H25NO4
I-Molar Mass 379.45
Ukuminyana 1.238
I-Melting Point 161-187 ℃
I-Boling Point 602.9±38.0 °C(Kubikezelwe)
Ukubukeka Impushana emhlophe ukuya kokumhlophe
pKa 3.89±0.10(Okubikezelwe)
Isimo Sesitoreji Kuvalwe endaweni eyomile, Ngezinga lokushisa Legumbi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ubungozi Nokuphepha

I-Hazard Class I-IRRITANT

I-Fmoc-D-Cyclohexyl glycine (CAS# 198543-96-3) Ulwazi

Sebenzisa I-Fluorene methoxycarbonyl D-cyclohexylglycine iyimithi evamile namakhemikhali aphakathi nendawo, i-fluorenyl chloride (FMOC-Cl) iyi-chloroformate. Isetshenziselwa ukwakha i-fluorene methoxycarbonyl (iqembu le-FMOC) ibe yi-fluorene methoxycarbonyl carbamate FMOC carbamate, okuyiqembu elivamile lokuvikela amino.
Ukulungiselela Ukuhlanganiswa kwe-fluorene methoxycarbonyl D-cyclohexylglycine kubikwe ezincwadini. Ukusebenzisa i-cyclohexyl bromide njengento eluhlaza, phambi kwe-sodium alkoxide, ithola ukusabela kwe-alkylation ne-diethyl malonate, bese i-hydrolyzes, i-acidifies, ne-decarboxylates ukuze ithole i-cyclohexyl acetic acid; eyokugcina ke i-brominated kanye ne-ammonolysis i-DL-Cyclohexylglycine; ekugcineni, ukusabela kwe-acylation kwenzeka phambi kwe-fluorene methoxycarbonyl chloride ukuze kutholwe i-fluorene methoxycarbonyl D-cyclohexylglycine [1]. Umzila wokusabela we-synthesis umi kanje:

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