FMOC-D-Ls(BOC)-OH(CAS# 92122-45-7)
| Izimpawu Eziyingozi | N – Iyingozi emvelweni |
| Amakhodi Engozi | 50/53 - Kunobuthi kakhulu ezintweni eziphila emanzini, kungabangela imiphumela emibi yesikhathi eside endaweni yasemanzini. |
| Incazelo Yokuphepha | S60 – Le nto kanye nesiqukathi sayo kumele kulahlwe njengemfucuza eyingozi. I-S61 - Gwema ukudedelwa endaweni. Bheka imiyalelo ekhethekile / amaphepha edatha okuphepha. I-S24/25 - Gwema ukuthintana nesikhumba namehlo. |
| I-WGK Germany | 3 |
| Ikhodi ye-HS | 29225090 |
Isingeniso
I-N(ε)-Boc-N(α)-i-lysine enezinhlangothi ezintathu (i-Fmoc-D-Lys(Boc)-OH) iphuma e-amino acid ehlanganisa i-molecule ye-lysine evikelwe kanye neqembu le-Fmoc. Nansi eminye imininingwane ngale nhlanganisela:
Imvelo:
-Ifomula yamakhemikhali: C24H29N3O6
Isisindo samangqamuzana: 455.50g/mol
-Ukubukeka: Ikristalu emhlophe noma i-crystalline powder
-indawo yokubanda: mayelana ne-120-126°C
-Ukunyibilika: Kuncibilika kwezinye izincibilikisi eziphilayo, njenge-dimethylthiourea (DMF), i-dimethylformamide (DMF) kanye nenani elincane le-ethanol
Sebenzisa:
I-Fmoc-D-Lys(Boc) -OH ingelinye lamaqembu avikela ama-amino acid asetshenziswa kakhulu ekuhlanganiseni kwesigaba esiqinile, esingasetshenziswa njengesiqalo sokuhlanganiswa kwama-polypeptides namaprotheni.
-Isetshenziswa kabanzi ocwaningweni lwezemithi, i-biochemistry kanye ne-protein synthesis
Indlela:
-Ukulungiswa kwe-Fmoc-D-Ls(Boc)-OH kuvame ukwenziwa ngezindlela zokuhlanganisa amakhemikhali ngaphansi kokuqondisa kwe-nuclear magnetic resonance. Le ndlela ibandakanya ukuvikelwa kwe-Fmoc kwe-Lys(Boc)-OH futhi ngokuvamile kwenziwa ngaphansi kwezimo eziyisisekelo. Umkhiqizo wokugcina utholakala nge-crystallization noma ukuhlanzwa.
Ulwazi Lokuphepha:
- I-Fmoc-D-Ls(Boc)-OH izinzile ngaphansi kwezimo ezijwayelekile zokusetshenziswa. Kodwa-ke, njengoba kuyikhemikhali, kusadingeka ukuthi unake izinyathelo zokusebenza eziphephile.
-Gwema ukuhogela, ukumunca noma ukuthinta isikhumba namehlo.
-Gqoka amagilavu okuzivikela, ukuvikela amehlo, kanye nejazi lelebhu elifanelekile ozolisebenzisa.
-Landela imithetho efanele yokuphepha yaselabhorethri kanye nemihlahlandlela yokusebenza lapho uphatha futhi ugcina amakhemikhali.
