FMOC-D-Valine (CAS# 84624-17-9)
| Incazelo Yokuphepha | S22 - Ungaphefumuli uthuli. I-S24/25 - Gwema ukuthintana nesikhumba namehlo. |
| I-WGK Germany | 3 |
| Ikhodi ye-HS | 2924 29 70 |
Isingeniso
I-fmoc-D-valine(fmoc-D-valine) iyi-reagent yamakhemikhali esetshenziswa kakhulu ekuhlanganiseni kwe-peptide kanye nobunjiniyela bamaprotheni ekuhlanganiseni kwesigaba esiqinile. Inezici ezilandelayo:
1. Izakhiwo zamakhemikhali: i-fmoc-D-valine iqinile emhlophe, ene-hydrophobic. Iyancibilika kuzincibilikisi eziphilayo njenge-dimethyl sulfoxide (DMSO) ne-methylene chloride, kodwa ayincibiliki kahle emanzini. Ifomula yayo yamangqamuzana yi-C21H23NO5 futhi isisindo sayo samangqamuzana ngu-369.41.
2. sebenzisa: i-fmoc-D-valine ingenye yezinto ezibalulekile zokusetshenziswa kwama-peptide namaprotheni, ingasetshenziselwa ukuhlanganiswa kwama-peptide asebenzayo biologically. Ivamise ukusetshenziswa ekuhlanganiseni kwesigaba esiqinile ukwakha amaketanga e-peptide ngokusabela kwe-condensation nezinye izinsalela ze-amino acid. Ngaphezu kwalokho, ingasetshenziswa futhi ukutadisha ukuhlanganiswa kwama-peptide asebenzayo kanye nokwakhiwa kwezidakamizwa.
3. Indlela yokulungiselela: Ukuhlanganiswa kwe-fmoc-D-valine kuvame ukwenziwa ngendlela yokuhlanganisa amakhemikhali. I-L-valine iqala ukusabela neqembu elivikelayo le-Fmoc ukuze kuvikelwe iqembu lama-amino ekusebenzeni kwamakhemikhali. Iqembu lokuvikela i-Fmoc libe selisuswa ukusabela kokuvikela ukunikeza i-fmoc-D-valine.
4. ulwazi lokuphepha: i-fmoc-D-valine inokuphepha okuhle ngaphansi kwezimo ezijwayelekile zokusetshenziswa, kodwa isadinga ukunaka lokhu okulandelayo: gwema ukuthintana nesikhumba namehlo, njengokuthintana ngephutha, kufanele ihlanzwe ngokushesha ngamanzi amaningi, futhi ufune usizo lwezokwelapha; Ngesikhathi sokusebenza kufanele banake umsoco kanye nenhlanzeko yomuntu siqu; isitoreji kufanele sivalwe, gwema ilanga eliqondile nendawo enomswakama. Uma usebenzisa, sicela ubheke imiyalelo yokuphepha efanele kanye namaphepha edatha yokuphepha kwezinto (MSDS).
