I-Fmoc-L-2-Aminobutyric acid (CAS# 135112-27-5 )

Incazelo Yokuphepha	S22 - Ungaphefumuli uthuli. I-S24/25 - Gwema ukuthintana nesikhumba namehlo.
I-WGK Germany	3
Ikhodi ye-HS	2924 29 70
I-Hazard Class	I-IRRITANT

I-L-2-(i-fluorenylmethoxycarbonylamino) i-butyric acid, eyaziwa nangokuthi i-Fmoc-glutamic acid (L-2-(9-fluorenylmethoxycarbonylamino) i-butyric acid), into ephilayo. Okulandelayo incazelo yezinye izakhiwo zayo, ukusetshenziswa, izindlela kanye nolwazi lokuphepha:

Imvelo:
-Ukubukeka: I-crystalline powder engenambala noma ephuzi kancane;
-Ifomula ye-molecular: C26H23NO4;
-Isisindo samangqamuzana: 413.47g / mol;
-indawo yokuncibilika: mayelana ne-166-168 ℃;
-I-Solubility: I-Fmoc-glutamic acid iyancibilika kuma-organic solvents afana ne-dimethylformamide ne-hydrofluoric acid.

Sebenzisa:
I-Fmoc-glutamic acid, njengenhlanganisela yeqembu elivikelayo, ivame ukusetshenziswa ekuhlanganiseni kwe-peptide, ikakhulukazi ekuhlanganisweni kokulandelana kwe-peptide ezinzile kanye nokuhlanganiswa kwe-Levenstein peptide (i-Levenshtein peptide). Ingasetshenziswa njenge-synthetic intermediate yama-amino acid, noma isetshenziswe ekuhlanganiseni kwesigaba esiqinile, ukusebenza okuphezulu kwe-chromatography ye-liquid, njll.

Indlela Yokulungiselela:
Ukulungiswa kwe-Fmoc-glutamic acid ngokuvamile kuhlanganisa lezi zinyathelo ezilandelayo:
1. Kuhlelo lwe-anhydrous, i-L-glutamic acid isabela nge-Fmoc-OSu (i-fluorenylmethoxycarbonyl-chloro anhydride), futhi i-sodium chloride (NaCl) isetshenziselwa ukukhuthaza ukusabela ukukhiqiza usawoti we-Fmoc-glutamic Fmoc-A.
2. Ngosawoti we-Fmoc-glutamic acid, uncibilika ku-solvent (njenge-dimethylformamide) futhi ungaphansi kwendlela yokuhlanza efanele (njenge-crystallization) ukuze kutholwe i-Fmoc-glutamic acid.

Ulwazi Lokuphepha:
I-Fmoc-glutamic acid ivamise ukuzinza futhi inobuthi obuphansi ngaphansi kokusebenza okujwayelekile. Kodwa njengenhlanganisela ye-organic, kusadingeka ukuthi unake izinyathelo zokuphepha ezilandelayo:
-Gwema ukuhogela uthuli, ukuthintana nesikhumba namehlo;
-Ngesikhathi sokusebenza, gqoka amagilavu ​​okuzivikela, izibuko nezingubo zokuzivikela ezihlangabezana nezidingo zokuphepha;
-Sebenzisa endaweni enomoya omuhle ukuze ugweme ukuchayeka okuqondile isikhathi eside;
-Uma imfucuza evela kule nhlanganisela izolahlwa, kufanele ilahlwe ngokufanele ngokuhambisana nemithetho yendawo.