I-Fmoc-L-aspartic acid (CAS# 119062-05-4)

I-Fmoc-L-aspartic acid iphuma ku-amino acid enezici ezilandelayo:

Ukubukeka: i-crystalline powder emhlophe noma emhlophe.
Ukunyibilika: Ukuncibilika okuhle kuzincibilikisi zemvelo (njenge-dimethyl sulfoxide, i-dimethylformamide), kodwa ukuncibilika okuncane emanzini.

I-Fmoc-L-aspartic acid inohlu olubanzi lwezinhlelo zokusebenza ocwaningweni lwe-biochemical and organic synthesis, futhi ukusetshenziswa okuyinhloko kungokulandelayo:

I-Peptide synthesis: I-Fmoc-L-aspartic acid ivame ukusetshenziswa ekuhlanganiseni kwesigaba esiqinile njengenye yamayunithi e-amino acid okuhlanganiswa kwama-peptides namaprotheni.
Ucwaningo lwebhayoloji: I-Fmoc-L-aspartic acid ingasetshenziswa ukutadisha ukwakheka nokusebenza kwamaprotheni, njengesakhiwo kanye nobudlelwano bomsebenzi wamaphrotheni ngokuhlanganisa ama-peptide ezicezu.

Indlela yokulungiselela i-Fmoc-L-aspartic acid ivame ukutholwa ngokusabela kwamakhemikhali ngokusebenzisa i-acetyl-L-aspartic acid ne-Fmoc-Cl (difluorothiophenolate) njengezinto zokusetshenziswa.

Ulwazi Lokuphepha: I-Fmoc-L-aspartic acid iyi-reagent evamile kumalabhorethri amakhemikhali, kodwa idinga ukusetshenziswa ngokuqapha. Lapho usebenza, kuyadingeka ukugqoka amagilavu ​​aselabhorethri, izibuko zokuzivikela, nezingubo zaselabhorethri ukugwema ukuthintana ngqo nesikhumba namehlo. Futhi, qaphela ukugwema ukuhogela impushana yomkhiqizo ukuze ugweme ukubangela ukucasuka kokuphefumula. Uma kwenzeka kuba nezingozi, usizo lokuqala olufanele kufanele luthathwe ngokushesha futhi kuboniswane nochwepheshe bezokwelapha.