FMOC-O-tert-Butyl-L-serine (CAS# 71989-33-8)
| Izimpawu Eziyingozi | Xi - Irritant |
| Amakhodi Engozi | 36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. |
| Incazelo Yokuphepha | I-S24/25 - Gwema ukuthintana nesikhumba namehlo. S36/37/39 – Gqoka izingubo zokuzivikela ezifanele, amagilavu kanye nokuvikela iso/ubuso. S27 – Khumula ngokushesha zonke izingubo ezingcolile. S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. |
| I-WGK Germany | 3 |
| Ikhodi ye-HS | 29242990 |
Isingeniso
I-FMOC-O-tert-butyl-L-serine iyinhlanganisela yezinto eziphilayo, futhi igama layo lamakhemikhali yi-epichlorotoluene serine. Okulandelayo yisingeniso sezakhiwo zayo, ukusetshenziswa kwayo, izindlela zokukhiqiza kanye nolwazi lokuphepha:
Ikhwalithi:
I-FMOC-O-tert-butyl-L-serine iqinile ngokubukeka okumhlophe kuya kokumhlophe. Ibola ngesisombululo futhi isengozini yomswakama.
Sebenzisa:
I-FMOC-O-tert-butyl-L-serine iyiqembu elivame ukusetshenziswa le-aminoprotective elisetshenziswa kakhulu ekuhlanganiseni ama-peptides namaprotheni. Ukusetshenziswa kwayo okuyinhloko njengeqembu elivikelayo lamaketanga e-peptide, ngokuvikela amaqembu e-amino ngesikhathi sokuhlanganiswa nokugwema ukusabela kwawo namanye amaqembu asebenzayo. Iphinde ibe nokuncibilika okuhle futhi ingasetshenziswa njenge-synthetic intermediate.
Indlela:
Ukulungiswa kwe-FMOC-O-tert-butyl-L-serine ngokuvamile kusebenzisa isu lokuvikela le-FOC elihlanganiswe nokusabela kweWick. I-Tert-butoxycarbonyl methylserine isabela nge-triethylamine kanye ne-tetraethyl disilicate ukuze yakhe i-FMOC-O-tert-butyl-L-serine. Indlela ethile yokuhlanganisa idinga ukwenziwa ngaphansi kwezimo ezifanele zaselabhorethri.
Ulwazi Lokuphepha:
Ukusetshenziswa kwe-FMOC-O-tert-butyl-L-serine kufanele kulandele izinqubo eziphephile. Ingase ibe nomthelela ocasulayo emehlweni, esikhumbeni, nasendleleni yokuphefumula ngendlela yayo emsulwa. Izinto zokuvikela ezifanele njengamagilavu, izibuko zokuphepha, nezinto zokuvikela ukuphefumula kufanele zigqokwe lapho zisetshenziswa. Kufanele igcinwe kude namalangabi avulekile kanye nemithombo yokushisa futhi isetshenziswe endaweni enomoya omuhle. Uma udliwe noma uhogelwe, funa usizo lwezokwelapha ngokushesha.
