Isingeniso
I-Fmoc-O-trityl-L-threonine iyinhlanganisela yemvelo enezakhiwo ezithile kanye nokusetshenziswa. Nalu olunye ulwazi olubalulekile:Izakhiwo: I-Fmoc-O-trityl-L-threonine iqinile emhlophe enefomula yamakhemikhali engu-C40H32N2O5 kanye nesisindo samangqamuzana esihlobene esingu-624.690g/mol. Inezinto ezizinzile futhi iyinhlanganisela encibilikayo kuma-non-polar solvents.Inhloso: I-Fmoc-O-trityl-L-threonine iyiqembu elivame ukusetshenziswa elivikela ama-amino acid, elisetshenziswa kakhulu ekuhlanganiseni kwe-peptide. Ingakwazi ukuvikela ngempumelelo iqembu le-amino le-L-threonine futhi ivimbele ukusabela okungafuneki phakathi nenqubo yokuhlanganiswa. Ngaphezu kwalokho, i-Fmoc-O-trityl-L-threonine ingasetshenziswa futhi njenge-reagent yokufunda ukusabela kwamakhemikhali e-organic.
Indlela yokulungiselela: Indlela yokulungiselela ye-Fmoc-O-trityl-L-threonine iyinkimbinkimbi futhi idinga uchungechunge lwezinyathelo zokusabela kwamakhemikhali. Indlela evamile yokulungiselela ukwethula iqembu le-Fmoc ngokusabela i-triphenylmethanol kanye ne-chloromethylating ejenti ku-L-threonine.
Ulwazi Lokuphepha: Qaphela ukuphepha lapho usebenzisa i-Fmoc-O-trityl-L-threonine. Kungase kucasule isikhumba, amehlo kanye nesistimu yokuphefumula. Gwema ukuthintana ngqo nesikhumba namehlo ngesikhathi sokuhlinzwa, futhi usebenzise elabhorethri engenawo umoya. Izimpahla zokuzivikela ezifanele ezifana namagilavu elebhu nezibuko kufanele zigqokwe ngesikhathi sokuphatha. Ngesikhathi sokugcina nokulahlwa, imisebenzi kufanele yenziwe ngokuhambisana nemithetho efanele yokuphepha kwamakhemikhali.
Okwedlule: I-5-Chloro-2 4-difluorobenzoic acid (CAS# 130025-33-1) Olandelayo: 3 4-DIBROMOPYRIDINE (CAS# 13534-90-2)
