I-Heptanoic acid,7-amino-, i-hydrochloride (1:1)(CAS#62643-56-5)

I-Heptanoic acid,7-amino-, i-hydrochloride (1:1)(CAS#62643-56-5)

I-Heptanoic acid,7-amino-, i-hydrochloride (1:1), inombolo ye-CAS 62643-56-5, inezici ezinganakwa kanye namandla okusebenza emikhakheni yamakhemikhali kanye ne-biomedicine.

Ngokwesakhiwo samakhemikhali, iyinhlanganisela eyakhiwe usawoti we-7-aminoheptanoic acid ne-hydrochloric acid ngesilinganiso se-1: 1. Iqembu le-amino ku-molecule linikeza i-alkalinity ethile, engahlanganiswa ne-hydrochloric acid ukuze kwakhiwe isakhiwo sikasawoti esizinzile, esingashintshi nje kuphela izakhiwo ezibonakalayo zento yokuqala, njengokuncibilika, indawo yokuncibilika, njll., kodwa futhi. iyenza izinze kakhulu ngesikhathi sokugcinwa nokusetshenziswa. Ukwakheka kwe-heptanoic acid enochungechunge olude kuletha i-hydrophobicity ku-molecule, ephikisana ne-hydrophilicity yeqembu lama-amino futhi yakhe isici esiyingqayizivele se-amphiphilic. Imvamisa yethulwa njengempushana emhlophe ecwebezelayo, leli fomu eliqinile lisiza ukucutshungulwa nokubunjwa kwamalungiselelo emithi, futhi liyasiza ekwenzeni amaphilisi, amaphilisi kanye namanye amafomu omthamo. Mayelana ne-solubility, inokuncibilika okuhle ngenxa yokwakheka kukasawoti emanzini, othuthukiswa kakhulu uma kuqhathaniswa ne-7-aminoheptanoic acid yamahhala, futhi ingabonisa ukuncibilika okusesilinganisweni kwezinye izinyibilikisi ze-polar organic, okunikeza lula ukusabela kwamakhemikhali okulandelayo kanye nokuhlanganiswa kwezidakamizwa. .
Kuzinhlelo zokusebenza ze-biomedical, kukhombisa amandla amakhulu. Njengento ephuma ku-amino acid, ingase ihileleke ezinqubweni ze-metabolic yomuntu noma njengesandulela sokuhlanganiswa kwama-molecule asebenza ngokwebhayoloji. Emkhakheni wokucwaninga nokuthuthukiswa kwezidakamizwa, ukwakheka kwawo kufana namanye ama-neurotransmitters aziwayo noma izinto eziphilayo, futhi kuyathembisa ukuthi ngokuqhubeka nokuguqulwa nokuguqulwa, izidakamizwa ezintsha zezifo zemizwa, njengesifo sikaParkinson, isithuthwane, njll., ithuthukiswe ukuze ibe nemiphumela yokwelapha ngokulawula izindlela zokubonisa izinzwa kanye nokwengeza ama-neurotransmitters. Ngaphezu kwalokho, emkhakheni wobunjiniyela bezicubu, ngokusekelwe ku-amphiphilia yayo eyingqayizivele kanye ne-biocompatibility, kulindeleke ukuthi isetshenziselwe ukwakha izinto ze-biomimetic ukukhuthaza ukunamathela kwamangqamuzana, ukwanda nokuhlukaniswa, nokusiza ukulungiswa nokuvuselelwa kwezicubu nezitho.
Ngokwendlela yokulungiselela, i-7-aminoheptanoic acid ngokuvamile ilungiswa nge-organic synthesis, bese i-hydrochloric acid yethulwa kusawoti ngokusabela kwe-acid-base neutralization. Inqubo yokuhlanganisa i-7-aminoheptanoic acid ihilela ukusabela okuphilayo okunezinyathelo eziningi, kusukela ezintweni ezingavuthiwe ezinjengama-fatty acids nama-amines, nokudlula ezinyathelweni ezifana nokunciphisa nokunciphisa.